Regulation of Sod Production in Lung Cells

Fanburg, Barry L.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 5R01HL042376-03
• Application #: 3360559
• Study Section: Respiratory and Applied Physiology Study Section (RAP)
• Project Start: 1989-04-01
• Project End: 1993-03-31
• Budget Start: 1991-04-01
• Budget End: 1993-03-31
• Support Year: 3
• Fiscal Year: 1991

Institution

• Name: Tufts University
• City: Boston
• State: MA
• Country: United States
• Zip Code: 02111

Publications

Day, Regina M; Suzuki, Yuichiro J; Lum, Julie M et al. (2002) Bleomycin upregulates expression of gamma-glutamylcysteine synthetase in pulmonary artery endothelial cells. Am J Physiol Lung Cell Mol Physiol 282:L1349-57

Larios, J M; Budhiraja, R; Fanburg, B L et al. (2001) Oxidative protein cross-linking reactions involving L-tyrosine in transforming growth factor-beta1-stimulated fibroblasts. J Biol Chem 276:17437-41

Thannickal, V J; Fanburg, B L (2000) Reactive oxygen species in cell signaling. Am J Physiol Lung Cell Mol Physiol 279:L1005-28

Finlay, G A; Thannickal, V J; Fanburg, B L et al. (2000) Transforming growth factor-beta 1-induced activation of the ERK pathway/activator protein-1 in human lung fibroblasts requires the autocrine induction of basic fibroblast growth factor. J Biol Chem 275:27650-6

Thannickal, V J; Day, R M; Klinz, S G et al. (2000) Ras-dependent and -independent regulation of reactive oxygen species by mitogenic growth factors and TGF-beta1. FASEB J 14:1741-8

White, A C; Maloney, E K; Lee, S L et al. (1999) Reduction of endothelial cell related TGFbeta activity by thiols. Endothelium 6:231-9

Thannickal, V J; Aldweib, K D; Fanburg, B L (1998) Tyrosine phosphorylation regulates H2O2 production in lung fibroblasts stimulated by transforming growth factor beta1. J Biol Chem 273:23611-5

Thannickal, V J; Aldweib, K D; Rajan, T et al. (1998) Upregulated expression of fibroblast growth factor (FGF) receptors by transforming growth factor-beta1 (TGF-beta1) mediates enhanced mitogenic responses to FGFs in cultured human lung fibroblasts. Biochem Biophys Res Commun 251:437-41

Kong, X J; Lee, S L; Lanzillo, J J et al. (1993) Cu,Zn superoxide dismutase in vascular cells: changes during cell cycling and exposure to hyperoxia. Am J Physiol 264:L365-75

Hertig, I A; Hassoun, P M; Zulueta, J J et al. (1993) Mechanism of basal and transforming growth factor beta 1 stimulated H2O2 release by endothelial cells. Trans Assoc Am Physicians 106:179-86