Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL044712-06
Application #
2221648
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1991-01-01
Project End
1999-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115
Kim, Kevin K; Sheppard, Dean; Chapman, Harold A (2018) TGF-?1 Signaling and Tissue Fibrosis. Cold Spring Harb Perspect Biol 10:
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Grove, Lisa M; Southern, Brian D; Jin, Tong H et al. (2014) Urokinase-type plasminogen activator receptor (uPAR) ligation induces a raft-localized integrin signaling switch that mediates the hypermotile phenotype of fibrotic fibroblasts. J Biol Chem 289:12791-804
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Xu, Pinglong; Bailey-Bucktrout, Samantha; Xi, Ying et al. (2014) Innate antiviral host defense attenuates TGF-? function through IRF3-mediated suppression of Smad signaling. Mol Cell 56:723-37
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Shum, Anthony K; Alimohammadi, Mohammad; Tan, Catherine L et al. (2013) BPIFB1 is a lung-specific autoantigen associated with interstitial lung disease. Sci Transl Med 5:206ra139
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Xi, Y; Wei, Y; Sennino, B et al. (2013) Identification of pY654-?-catenin as a critical co-factor in hypoxia-inducible factor-1? signaling and tumor responses to hypoxia. Oncogene 32:5048-57
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