Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL044721-12
Application #
6400776
Study Section
Special Emphasis Panel (ZRG1-PTHA (03))
Program Officer
Lin, Michael
Project Start
1991-08-01
Project End
2005-07-31
Budget Start
2001-08-27
Budget End
2002-07-31
Support Year
12
Fiscal Year
2001
Total Cost
$319,000
Indirect Cost

  Institution

Name
University of Rochester
Department
Internal Medicine/Medicine
Type
Schools of Dentistry
DUNS #
208469486
City
Rochester
State
NY
Country
United States
Zip Code
14627

  Publications

Maekawa, Naoya; Abe, Jun-ichi; Shishido, Tetsuro et al. (2006) Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury. Circulation 113:2516-23
Itoh, Seigo; Ding, Bo; Shishido, Tetsuro et al. (2006) Role of p90 ribosomal S6 kinase-mediated prorenin-converting enzyme in ischemic and diabetic myocardium. Circulation 113:1787-98
Jin, Z G; Berk, B C (2004) SOXF: redox mediators of vascular smooth muscle cell growth. Heart 90:488-90
Osawa, Masaki; Itoh, Seigo; Ohta, Shinsuke et al. (2004) ERK1/2 associates with the c-Met-binding domain of growth factor receptor-bound protein 2 (Grb2)-associated binder-1 (Gab1): role in ERK1/2 and early growth response factor-1 (Egr-1) nuclear accumulation. J Biol Chem 279:29691-9
Akaike, Masashi; Che, Wenyi; Marmarosh, Nicole-Lerner et al. (2004) The hinge-helix 1 region of peroxisome proliferator-activated receptor gamma1 (PPARgamma1) mediates interaction with extracellular signal-regulated kinase 5 and PPARgamma1 transcriptional activation: involvement in flow-induced PPARgamma activation in end Mol Cell Biol 24:8691-704
Jin, Z G; Berk, B C (2004) Role of secreted oxidative stress-induced factors (SOXFs) in the pathogenesis of atherosclerosis. Arch Mal Coeur Vaiss 97:1256-9
Cavet, Megan E; Lehoux, Stephanie; Berk, Bradford C (2003) 14-3-3beta is a p90 ribosomal S6 kinase (RSK) isoform 1-binding protein that negatively regulates RSK kinase activity. J Biol Chem 278:18376-83
Huang, Qunhua; Lerner-Marmarosh, Nicole; Che, Wenyi et al. (2002) The novel role of the C-terminal region of SHP-2. Involvement of Gab1 and SHP-2 phosphatase activity in Elk-1 activation. J Biol Chem 277:29330-41
Che, Wenyi; Lerner-Marmarosh, Nicole; Huang, Qunhua et al. (2002) Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells: role of Gab1 and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression. Circ Res 90:1222-30
Takeishi, Yasuchika; Huang, Qunhua; Abe, Jun-ichi et al. (2002) Activation of mitogen-activated protein kinases and p90 ribosomal S6 kinase in failing human hearts with dilated cardiomyopathy. Cardiovasc Res 53:131-7

Showing the most recent 10 out of 35 publications