Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
3R01HL045422-05S1
Application #
2222137
Study Section
Special Emphasis Panel (SRC (DW))
Project Start
1990-07-01
Project End
1995-04-30
Budget Start
1994-05-01
Budget End
1995-04-30
Support Year
5
Fiscal Year
1994
Total Cost
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Salmon, Morgan; Owens, Gary K; Zehner, Zendra E (2009) Over-expression of the transcription factor, ZBP-89, leads to enhancement of the C2C12 myogenic program. Biochim Biophys Acta 1793:1144-55
Salmon, Morgan; Zehner, Zendra E (2009) The transcriptional repressor ZBP-89 and the lack of Sp1/Sp3, c-Jun and Stat3 are important for the down-regulation of the vimentin gene during C2C12 myogenesis. Differentiation 77:492-504
Wu, Yongzhong; Zhang, Xueping; Salmon, Morgan et al. (2007) The zinc finger repressor, ZBP-89, recruits histone deacetylase 1 to repress vimentin gene expression. Genes Cells 12:905-18
Wu, Yongzhong; Zhang, Xueping; Salmon, Morgan et al. (2007) TGFbeta1 regulation of vimentin gene expression during differentiation of the C2C12 skeletal myogenic cell line requires Smads, AP-1 and Sp1 family members. Biochim Biophys Acta 1773:427-39
Wu, Yongzhong; Diab, Iman; Zhang, Xueping et al. (2004) Stat3 enhances vimentin gene expression by binding to the antisilencer element and interacting with the repressor protein, ZBP-89. Oncogene 23:168-78
Brule, Herve; Elliott, Mark; Redlak, Maria et al. (2004) Isolation and characterization of the human tRNA-(N1G37) methyltransferase (TRM5) and comparison to the Escherichia coli TrmD protein. Biochemistry 43:9243-55
Zhang, Xueping; Diab, Iman H; Zehner, Zendra E (2003) ZBP-89 represses vimentin gene transcription by interacting with the transcriptional activator, Sp1. Nucleic Acids Res 31:2900-14
Wu, Yongzhong; Zhang, Xueping; Zehner, Zendra E (2003) c-Jun and the dominant-negative mutant, TAM67, induce vimentin gene expression by interacting with the activator Sp1. Oncogene 22:8891-901
Liu, Xuhui; Wu, Yongzhong; Zehner, Zendra E et al. (2003) Proteomic analysis of the tumorigenic human prostate cell line M12 after microcell-mediated transfer of chromosome 19 demonstrates reduction of vimentin. Electrophoresis 24:3445-53
Al-Maghrebi, May; Brule, Herve; Padkina, Marina et al. (2002) The 3' untranslated region of human vimentin mRNA interacts with protein complexes containing eEF-1gamma and HAX-1. Nucleic Acids Res 30:5017-28

Showing the most recent 10 out of 22 publications