Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL045967-06
Application #
2222591
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1990-09-30
Project End
2001-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
University of Cincinnati
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221

  Publications

Liggett, Stephen B (2018) Genetic Vulnerability of GPCRs: A Call to Action. Trends Biochem Sci 43:227-229
Kim, Donghwa; Cho, Soomin; Woo, Jung A et al. (2018) A CREB-mediated increase in miRNA let-7f during prolonged ?-agonist exposure: a novel mechanism of ?2-adrenergic receptor down-regulation in airway smooth muscle. FASEB J 32:3680-3688
An, Steven S; Liggett, Stephen B (2018) Taste and smell GPCRs in the lung: Evidence for a previously unrecognized widespread chemosensory system. Cell Signal 41:82-88
Kim, Donghwa; Woo, Jung A; Geffken, Ezekiel et al. (2017) Coupling of Airway Smooth Muscle Bitter Taste Receptors to Intracellular Signaling and Relaxation Is via G?i1,2,3. Am J Respir Cell Mol Biol 56:762-771
Aisenberg, William H; Huang, Jessie; Zhu, Wanqu et al. (2016) Defining an olfactory receptor function in airway smooth muscle cells. Sci Rep 6:38231
Kim, Donghwa; Pauer, Susan H; Yong, Hwan M et al. (2016) ?2-Adrenergic Receptors Chaperone Trapped Bitter Taste Receptor 14 to the Cell Surface as a Heterodimer and Exert Unidirectional Desensitization of Taste Receptor Function. J Biol Chem 291:17616-28
Koziol-White, Cynthia J; Yoo, Edwin J; Cao, Gaoyuan et al. (2016) Inhibition of PI3K promotes dilation of human small airways in a rho kinase-dependent manner. Br J Pharmacol 173:2726-38
An, Steven S; Mitzner, Wayne; Tang, Wan-Yee et al. (2016) An inflammation-independent contraction mechanophenotype of airway smooth muscle in asthma. J Allergy Clin Immunol 138:294-297.e4
Camoretti-Mercado, Blanca; Pauer, Susan H; Yong, Hwan Mee et al. (2015) Pleiotropic Effects of Bitter Taste Receptors on [Ca2+]i Mobilization, Hyperpolarization, and Relaxation of Human Airway Smooth Muscle Cells. PLoS One 10:e0131582
Wang, Wayne C H; Pauer, Susan H; Smith, Dan'elle C et al. (2014) Targeted transgenesis identifies G?s as the bottleneck in ?2-adrenergic receptor cell signaling and physiological function in airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 307:L775-80

Showing the most recent 10 out of 79 publications