Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL046764-10
Application #
6537002
Study Section
Cardiovascular and Pulmonary Research A Study Section (CVA)
Program Officer
Lathrop, David A
Project Start
1991-08-16
Project End
2005-04-30
Budget Start
2002-05-01
Budget End
2003-04-30
Support Year
10
Fiscal Year
2002
Total Cost
$362,500
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Ren, Zuojun; Raucci Jr, Frank J; Browe, David M et al. (2008) Regulation of swelling-activated Cl(-) current by angiotensin II signalling and NADPH oxidase in rabbit ventricle. Cardiovasc Res 77:73-80
Browe, David M; Baumgarten, Clive M (2006) EGFR kinase regulates volume-sensitive chloride current elicited by integrin stretch via PI-3K and NADPH oxidase in ventricular myocytes. J Gen Physiol 127:237-51
Baumgarten, Clive M (2006) Cell volume regulation in cardiac myocytes: a leaky boat gets a new bilge pump. J Gen Physiol 128:487-9
Ren, Zuojun; Baumgarten, Clive M (2005) Antagonistic regulation of swelling-activated Cl- current in rabbit ventricle by Src and EGFR protein tyrosine kinases. Am J Physiol Heart Circ Physiol 288:H2628-36
Browe, David M; Baumgarten, Clive M (2004) Angiotensin II (AT1) receptors and NADPH oxidase regulate Cl- current elicited by beta1 integrin stretch in rabbit ventricular myocytes. J Gen Physiol 124:273-87
Du, Xin-Ling; Gao, Zhan; Lau, Chu-Pak et al. (2004) Differential effects of tyrosine kinase inhibitors on volume-sensitive chloride current in human atrial myocytes: evidence for dual regulation by Src and EGFR kinases. J Gen Physiol 123:427-39
Browe, David M; Baumgarten, Clive M (2003) Stretch of beta 1 integrin activates an outwardly rectifying chloride current via FAK and Src in rabbit ventricular myocytes. J Gen Physiol 122:689-702
Baumgarten, Clive M; Clemo, Henry F (2003) Swelling-activated chloride channels in cardiac physiology and pathophysiology. Prog Biophys Mol Biol 82:25-42
Li, Gui-Rong; Zhang, Min; Satin, Leslie S et al. (2002) Biphasic effects of cell volume on excitation-contraction coupling in rabbit ventricular myocytes. Am J Physiol Heart Circ Physiol 282:H1270-7
Li, G R; Baumgarten, C M (2001) Modulation of cardiac Na(+) current by gadolinium, a blocker of stretch-induced arrhythmias. Am J Physiol Heart Circ Physiol 280:H272-9

Showing the most recent 10 out of 29 publications