Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL047125-10
Application #
6266895
Study Section
Lung Biology and Pathology Study Section (LBPA)
Program Officer
Banks-Schlegel, Susan P
Project Start
1991-01-07
Project End
2005-05-31
Budget Start
2001-06-01
Budget End
2002-05-31
Support Year
10
Fiscal Year
2001
Total Cost
$297,000
Indirect Cost

  Institution

Name
University of Maryland Baltimore
Department
Other Health Professions
Type
Schools of Pharmacy
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201

  Publications

Kato, Kosuke; Zemskova, Marina A; Hanss, Alec D et al. (2017) Muc1 deficiency exacerbates pulmonary fibrosis in a mouse model of silicosis. Biochem Biophys Res Commun 493:1230-1235
Kato, Kosuke; Hanss, Alec D; Zemskova, Marina A et al. (2017) Pseudomonas aeruginosa increases MUC1 expression in macrophages through the TLR4-p38 pathway. Biochem Biophys Res Commun 492:231-235
Xu, Xiuling; Chen, Wenshu; Leng, Shuguang et al. (2017) Muc1 knockout potentiates murine lung carcinogenesis involving an epiregulin-mediated EGFR activation feedback loop. Carcinogenesis 38:604-614
Kato, Kosuke; Uchino, Reina; Lillehoj, Erik P et al. (2016) Membrane-Tethered MUC1 Mucin Counter-Regulates the Phagocytic Activity of Macrophages. Am J Respir Cell Mol Biol 54:515-23
Kato, Kosuke; Lillehoj, Erik P; Kim, Kwang Chul (2016) Pseudomonas aeruginosa stimulates tyrosine phosphorylation of and TLR5 association with the MUC1 cytoplasmic tail through EGFR activation. Inflamm Res 65:225-33
Lillehoj, Erik P; Hyun, Sang Won; Liu, Anguo et al. (2015) NEU1 Sialidase Regulates Membrane-tethered Mucin (MUC1) Ectodomain Adhesiveness for Pseudomonas aeruginosa and Decoy Receptor Release. J Biol Chem 290:18316-31
Xu, Xiuling; Wells, Alexandria; Padilla, Mabel T et al. (2014) A signaling pathway consisting of miR-551b, catalase and MUC1 contributes to acquired apoptosis resistance and chemoresistance. Carcinogenesis 35:2457-66
Xu, Xiuling; Padilla, Mabel T; Li, Bilan et al. (2014) MUC1 in macrophage: contributions to cigarette smoke-induced lung cancer. Cancer Res 74:460-70
Kato, Kosuke; Lillehoj, Erik P; Kim, Kwang Chul (2014) MUC1 regulates epithelial inflammation and apoptosis by PolyI:C through inhibition of Toll/IL-1 receptor-domain-containing adapter-inducing IFN-? (TRIF) recruitment to Toll-like receptor 3. Am J Respir Cell Mol Biol 51:446-54
Guang, Wei; Czinn, Steven J; Blanchard, Thomas G et al. (2014) Genetic regulation of MUC1 expression by Helicobacter pylori in gastric cancer cells. Biochem Biophys Res Commun 445:145-50

Showing the most recent 10 out of 57 publications