Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL047186-05
Application #
2223480
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1991-09-01
Project End
1999-01-31
Budget Start
1996-02-01
Budget End
1997-01-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Pennsylvania
Department
Surgery
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Khan, Mohammad M H; Hattori, Takashi; Niewiarowski, Stefan et al. (2006) Truncated and microparticle-free soluble tissue factor bound to peripheral monocytes preferentially activate factor VII. Thromb Haemost 95:462-8
Hattori, Takashi; Khan, Mohammad M H; Colman, Robert W et al. (2005) Plasma tissue factor plus activated peripheral mononuclear cells activate factors VII and X in cardiac surgical wounds. J Am Coll Cardiol 46:707-13
Edmunds Jr, L Henry (2003) Advances in the heart-lung machine after John and Mary Gibbon. Ann Thorac Surg 76:S2220-3
Edmunds Jr, L Henry (2002) The evolution of cardiopulmonary bypass: lessons to be learned. Perfusion 17:243-51
Edmunds Jr, L H (2001) Evolution of prosthetic heart valves. Am Heart J 141:849-55
Selim, T E; Ghoneim, H R; Abdel Ghaffar, H A et al. (2001) High molecular mass kininogen inhibits cathepsin G-induced platelet activation by forming a complex with cathepsin G. Hematol J 2:371-7
Soulika, A M; Khan, M M; Hattori, T et al. (2000) Inhibition of heparin/protamine complex-induced complement activation by Compstatin in baboons. Clin Immunol 96:212-21
Suzuki, Y; Malekan, R; Hanson 3rd, C W et al. (1999) Platelet anesthesia with nitric oxide with or without eptifibatide during cardiopulmonary bypass in baboons. J Thorac Cardiovasc Surg 117:987-93
Khan, M M; Gikakis, N; Miyamoto, S et al. (1999) Aprotinin inhibits thrombin formation and monocyte tissue factor in simulated cardiopulmonary bypass. Ann Thorac Surg 68:473-8
Rao, A K; Sun, L; Hiramatsu, Y et al. (1999) Glycoprotein IIb/IIIa receptor antagonist tirofiban inhibits thrombin generation during cardiopulmonary bypass in baboons. Thromb Haemost 82:140-4

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