Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
2R01HL047811-05
Application #
2223897
Study Section
General Medicine B Study Section (GMB)
Project Start
1993-02-01
Project End
2000-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
5
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Qian, Jin; Colbert, Melissa C; Witte, David et al. (2003) Midgestational lethality in mice lacking the parathyroid hormone (PTH)/PTH-related peptide receptor is associated with abrupt cardiomyocyte death. Endocrinology 144:1053-61
Noonan, William T; Qian, Jin; Stuart, William D et al. (2003) Altered renal hemodynamics in mice overexpressing the parathyroid hormone (PTH)/PTH-related peptide type 1 receptor in smooth muscle. Endocrinology 144:4931-8
Clemens, T L; Qian, J; Colbert, M C (2001) Editorial: prenatal lethality in PTH type I receptor null mice--interrogating the usual suspects. Endocrinology 142:5056-8
Stuart, W D; Maeda, S; Khera, P et al. (2000) Parathyroid hormone-related protein induces G1 phase growth arrest of vascular smooth muscle cells. Am J Physiol Endocrinol Metab 279:E60-7
Maeda, S; Sutliff, R L; Qian, J et al. (1999) Targeted overexpression of parathyroid hormone-related protein (PTHrP) to vascular smooth muscle in transgenic mice lowers blood pressure and alters vascular contractility. Endocrinology 140:1815-25
Qian, J; Lorenz, J N; Maeda, S et al. (1999) Reduced blood pressure and increased sensitivity of the vasculature to parathyroid hormone-related protein (PTHrP) in transgenic mice overexpressing the PTH/PTHrP receptor in vascular smooth muscle. Endocrinology 140:1826-33
Sutliff, R L; Weber, C S; Qian, J et al. (1999) Vasorelaxant properties of parathyroid hormone-related protein in the mouse: evidence for endothelium involvement independent of nitric oxide formation. Endocrinology 140:2077-83
Tam, V K; Clemens, T L; Green, J (1998) The effect of cell-matrix interaction on parathyroid hormone (PTH) receptor binding and PTH responsiveness in proximal renal tubular cells and osteoblast-like cells. Endocrinology 139:3072-80
Maeda, S; Wu, S; Green, J et al. (1998) The N-terminal portion of parathyroid hormone-related protein mediates the inhibition of apical Na+/H+ exchange in opossum kidney cells. J Am Soc Nephrol 9:175-81
Vu, D; Ong, J M; Clemens, T L et al. (1996) 1,25-Dihydroxyvitamin D induces lipoprotein lipase expression in 3T3-L1 cells in association with adipocyte differentiation. Endocrinology 137:1540-4

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