Riewald, Matthias; Ruf, Wolfram (2005) Protease-activated receptor-1 signaling by activated protein C in cytokine-perturbed endothelial cells is distinct from thrombin signaling. J Biol Chem 280:19808-14
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Ahamed, Jasimuddin; Ruf, Wolfram (2004) Protease-activated receptor 2-dependent phosphorylation of the tissue factor cytoplasmic domain. J Biol Chem 279:23038-44
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Ruf, Wolfram (2004) Protease-activated receptor signaling in the regulation of inflammation. Crit Care Med 32:S287-92
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Ruf, W; Dorfleutner, A; Riewald, M (2003) Specificity of coagulation factor signaling. J Thromb Haemost 1:1495-503
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Ruf, Wolfram; Riewald, Matthias (2003) Tissue factor-dependent coagulation protease signaling in acute lung injury. Crit Care Med 31:S231-7
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Petrovan, Ramona J; Ruf, Wolfram (2002) Role of zymogenicity-determining residues of coagulation factor VII/VIIa in cofactor interaction and macromolecular substrate recognition. Biochemistry 41:9302-9
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Riewald, M; Ruf, W (2001) Mechanistic coupling of protease signaling and initiation of coagulation by tissue factor. Proc Natl Acad Sci U S A 98:7742-7
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Petrovan, R J; Ruf, W (2001) Residue Met(156) contributes to the labile enzyme conformation of coagulation factor VIIa. J Biol Chem 276:6616-20
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Petrovan, R J; Ruf, W (2000) Role of residue Phe225 in the cofactor-mediated, allosteric regulation of the serine protease coagulation factor VIIa. Biochemistry 39:14457-63
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Baugh, R J; Dickinson, C D; Ruf, W et al. (2000) Exosite interactions determine the affinity of factor X for the extrinsic Xase complex. J Biol Chem 275:28826-33
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