Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL049040-02
Application #
3368151
Study Section
Special Emphasis Panel (SRC (MP))
Project Start
1992-08-01
Project End
1997-06-30
Budget Start
1993-06-25
Budget End
1993-07-31
Support Year
2
Fiscal Year
1992
Total Cost
Indirect Cost

  Institution

Name
University of Pennsylvania
Department
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104

  Publications

Zhang, Zhe; Reenstra, William; Weiner, Daniel J et al. (2007) The p38 mitogen-activated protein kinase signaling pathway is coupled to Toll-like receptor 5 to mediate gene regulation in response to Pseudomonas aeruginosa infection in human airway epithelial cells. Infect Immun 75:5985-92
Kobinger, Gary P; Limberis, Maria P; Somanathan, Suri et al. (2007) Human immunodeficiency viral vector pseudotyped with the spike envelope of severe acute respiratory syndrome coronavirus transduces human airway epithelial cells and dendritic cells. Hum Gene Ther 18:413-22
Bell, Peter; Vandenberghe, Luk H; Wu, Di et al. (2007) A comparative analysis of novel fluorescent proteins as reporters for gene transfer studies. J Histochem Cytochem 55:931-9
Zhang, Zhe; Louboutin, Jean-Pierre; Weiner, Daniel J et al. (2005) Human airway epithelial cells sense Pseudomonas aeruginosa infection via recognition of flagellin by Toll-like receptor 5. Infect Immun 73:7151-60
Bals, R; Wilson, J M (2003) Cathelicidins--a family of multifunctional antimicrobial peptides. Cell Mol Life Sci 60:711-20
Medina, Maria Fe; Kobinger, Gary P; Rux, John et al. (2003) Lentiviral vectors pseudotyped with minimal filovirus envelopes increased gene transfer in murine lung. Mol Ther 8:777-89
Wang, Xiaorong; Moser, Christian; Louboutin, Jean-Pierre et al. (2002) Toll-like receptor 4 mediates innate immune responses to Haemophilus influenzae infection in mouse lung. J Immunol 168:810-5
Moser, Christian; Weiner, Daniel J; Lysenko, Elena et al. (2002) beta-Defensin 1 contributes to pulmonary innate immunity in mice. Infect Immun 70:3068-72
Croyle, Maria A; Chirmule, Narendra; Zhang, Yi et al. (2002) PEGylation of E1-deleted adenovirus vectors allows significant gene expression on readministration to liver. Hum Gene Ther 13:1887-900
Bals, R; Weiner, D J; Meegalla, R L et al. (2001) Salt-independent abnormality of antimicrobial activity in cystic fibrosis airway surface fluid. Am J Respir Cell Mol Biol 25:21-5

Showing the most recent 10 out of 22 publications