Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
7R01HL050545-11
Application #
6887927
Study Section
Hematology Subcommittee 2 (HEM)
Project Start
1994-05-01
Project End
2007-11-30
Budget Start
2004-07-01
Budget End
2004-11-30
Support Year
11
Fiscal Year
2004
Total Cost
$25,244
Indirect Cost
Name
University of Arkansas for Medical Sciences
Department
Physiology
Type
Schools of Medicine
DUNS #
122452563
City
Little Rock
State
AR
Country
United States
Zip Code
72205
Franco, Aime T; Corken, Adam; Ware, Jerry (2015) Platelets at the interface of thrombosis, inflammation, and cancer. Blood 126:582-8
Corken, Adam; Russell, Susan; Dent, Judith et al. (2014) Platelet glycoprotein Ib-IX as a regulator of systemic inflammation. Arterioscler Thromb Vasc Biol 34:996-1001
Kanaji, S; Fahs, S A; Ware, J et al. (2014) Non-myeloablative conditioning with busulfan before hematopoietic stem cell transplantation leads to phenotypic correction of murine Bernard-Soulier syndrome. J Thromb Haemost 12:1726-32
Boulaftali, Yacine; Hess, Paul R; Getz, Todd M et al. (2013) Platelet ITAM signaling is critical for vascular integrity in inflammation. J Clin Invest 123:908-16
Joglekar, M V; Ware, Jerry; Xu, Jin et al. (2013) Platelets, glycoprotein Ib-IX, and von Willebrand factor are required for FeCl(3)-induced occlusive thrombus formation in the inferior vena cava of mice. Platelets 24:205-12
Ware, Jerry; Corken, Adam; Khetpal, Reshma (2013) Platelet function beyond hemostasis and thrombosis. Curr Opin Hematol 20:451-6
Yin, Hong; Stojanovic-Terpo, Aleksandra; Xu, Weidong et al. (2013) Role for platelet glycoprotein Ib-IX and effects of its inhibition in endotoxemia-induced thrombosis, thrombocytopenia, and mortality. Arterioscler Thromb Vasc Biol 33:2529-37
Kanaji, Taisuke; Ware, Jerry; Okamura, Takashi et al. (2012) GPIb? regulates platelet size by controlling the subcellular localization of filamin. Blood 119:2906-13
Boilard, Eric; Larabee, Katherine; Shnayder, Ruslan et al. (2011) Platelets participate in synovitis via Cox-1-dependent synthesis of prostacyclin independently of microparticle generation. J Immunol 186:4361-6
Boilard, Eric; Nigrovic, Peter A; Larabee, Katherine et al. (2010) Platelets amplify inflammation in arthritis via collagen-dependent microparticle production. Science 327:580-3

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