Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL051854-03
Application #
2228846
Study Section
Lung Biology and Pathology Study Section (LBPA)
Project Start
1994-04-08
Project End
1998-03-31
Budget Start
1996-04-01
Budget End
1997-03-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of California San Francisco
Department
Internal Medicine/Medicine
Type
Schools of Medicine
DUNS #
073133571
City
San Francisco
State
CA
Country
United States
Zip Code
94143
Gotts, Jeffrey E; Abbott, Jason; Fang, Xiaohui et al. (2017) Cigarette Smoke Exposure Worsens Endotoxin-Induced Lung Injury and Pulmonary Edema in Mice. Nicotine Tob Res 19:1033-1039
Jackson, Megan V; Morrison, Thomas J; Doherty, Declan F et al. (2016) Mitochondrial Transfer via Tunneling Nanotubes is an Important Mechanism by Which Mesenchymal Stem Cells Enhance Macrophage Phagocytosis in the In Vitro and In Vivo Models of ARDS. Stem Cells 34:2210-23
Hendrickson, Carolyn M; Crestani, Bruno; Matthay, Michael A (2015) Biology and pathology of fibroproliferation following the acute respiratory distress syndrome. Intensive Care Med 41:147-50
McAuley, D F; Curley, G F; Hamid, U I et al. (2014) Clinical grade allogeneic human mesenchymal stem cells restore alveolar fluid clearance in human lungs rejected for transplantation. Am J Physiol Lung Cell Mol Physiol 306:L809-15
Gotts, Jeffrey E; Abbott, Jason; Matthay, Michael A (2014) Influenza causes prolonged disruption of the alveolar-capillary barrier in mice unresponsive to mesenchymal stem cell therapy. Am J Physiol Lung Cell Mol Physiol 307:L395-406
Zhu, Ying-Gang; Feng, Xiao-Mei; Abbott, Jason et al. (2014) Human mesenchymal stem cell microvesicles for treatment of Escherichia coli endotoxin-induced acute lung injury in mice. Stem Cells 32:116-25
Greer, Alexandra M; Matthay, Michael A; Kukreja, Jasleen et al. (2014) Accumulation of BDCA1? dendritic cells in interstitial fibrotic lung diseases and Th2-high asthma. PLoS One 9:e99084
Walter, James; Ware, Lorraine B; Matthay, Michael A (2014) Mesenchymal stem cells: mechanisms of potential therapeutic benefit in ARDS and sepsis. Lancet Respir Med 2:1016-26
Gotts, Jeffrey E; Matthay, Michael A (2014) Endogenous and exogenous cell-based pathways for recovery from acute respiratory distress syndrome. Clin Chest Med 35:797-809
Goolaerts, Arnaud; Pellan-Randrianarison, Nadia; Larghero, Jérôme et al. (2014) Conditioned media from mesenchymal stromal cells restore sodium transport and preserve epithelial permeability in an in vitro model of acute alveolar injury. Am J Physiol Lung Cell Mol Physiol 306:L975-85

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