Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL054131-03
Application #
2232375
Study Section
Pathology A Study Section (PTHA)
Project Start
1994-08-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
3
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Yale University
Department
Pathology
Type
Schools of Medicine
DUNS #
082359691
City
New Haven
State
CT
Country
United States
Zip Code
06520
Chae, Young Chan; Angelin, Alessia; Lisanti, Sofia et al. (2013) Landscape of the mitochondrial Hsp90 metabolome in tumours. Nat Commun 4:2139
Vaira, Valentina; Faversani, Alice; Martin, Nina M et al. (2013) Regulation of lung cancer metastasis by Klf4-Numb-like signaling. Cancer Res 73:2695-705
Altieri, Dario C (2013) Targeting survivin in cancer. Cancer Lett 332:225-8
Caino, M Cecilia; Chae, Young Chan; Vaira, Valentina et al. (2013) Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells. J Clin Invest 123:2907-20
Vaira, V; Faversani, A; Dohi, T et al. (2012) miR-296 regulation of a cell polarity-cell plasticity module controls tumor progression. Oncogene 31:27-38
Chae, Young Chan; Caino, M Cecilia; Lisanti, Sofia et al. (2012) Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s. Cancer Cell 22:331-44
Yu, Jun; Zhang, Yuanyuan; Zhang, Xinbo et al. (2012) Endothelium derived nitric oxide synthase negatively regulates the PDGF-survivin pathway during flow-dependent vascular remodeling. PLoS One 7:e31495
Kang, Byoung Heon; Xia, Fang; Pop, Ramona et al. (2011) Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein. J Biol Chem 286:16758-67
Siegelin, Markus D; Dohi, Takehiko; Raskett, Christopher M et al. (2011) Exploiting the mitochondrial unfolded protein response for cancer therapy in mice and human cells. J Clin Invest 121:1349-60
Altieri, Dario C (2011) Mitochondrial compartmentalized protein folding and tumor cell survival. Oncotarget 2:347-51

Showing the most recent 10 out of 108 publications