Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL054176-07
Application #
6537176
Study Section
Nutrition Study Section (NTN)
Program Officer
Ershow, Abby
Project Start
1996-03-01
Project End
2004-03-31
Budget Start
2002-04-01
Budget End
2003-03-31
Support Year
7
Fiscal Year
2002
Total Cost
$362,500
Indirect Cost

  Institution

Name
Wake Forest University Health Sciences
Department
Pathology
Type
Schools of Medicine
DUNS #
937727907
City
Winston-Salem
State
NC
Country
United States
Zip Code
27157

  Publications

Chung, Soonkyu; Gebre, Abraham K; Seo, Jeongmin et al. (2010) A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretion. J Lipid Res 51:729-42
Mulya, Anny; Seo, Jeongmin; Brown, Amanda L et al. (2010) Apolipoprotein M expression increases the size of nascent pre beta HDL formed by ATP binding cassette transporter A1. J Lipid Res 51:514-24
Chung, Soonkyu; Timmins, Jenelle M; Duong, Myngan et al. (2010) Targeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolism. J Biol Chem 285:12197-209
Cheng, Dongmei; MacArthur, Philip S; Rong, Shunxing et al. (2010) Alternative splicing attenuates transgenic expression directed by the apolipoprotein E promoter-enhancer based expression vector pLIV11. J Lipid Res 51:849-55
Hirsch-Reinshagen, Veronica; Donkin, James; Stukas, Sophie et al. (2009) LCAT synthesized by primary astrocytes esterifies cholesterol on glia-derived lipoproteins. J Lipid Res 50:885-93
Domoki, Ferenc; Kis, Bela; Gaspar, Tamas et al. (2008) Cerebromicrovascular endothelial cells are resistant to L-glutamate. Am J Physiol Regul Integr Comp Physiol 295:R1099-108
Mulya, Anny; Lee, Ji-Young; Gebre, Abraham K et al. (2008) Initial interaction of apoA-I with ABCA1 impacts in vivo metabolic fate of nascent HDL. J Lipid Res 49:2390-401
Zhu, Xuewei; Lee, Ji-Young; Timmins, Jenelle M et al. (2008) Increased cellular free cholesterol in macrophage-specific Abca1 knock-out mice enhances pro-inflammatory response of macrophages. J Biol Chem 283:22930-41
Wu, Zhiping; Wagner, Matthew A; Zheng, Lemin et al. (2007) The refined structure of nascent HDL reveals a key functional domain for particle maturation and dysfunction. Nat Struct Mol Biol 14:861-8
Lee, Ji-Young; Badeau, Robert M; Mulya, Anny et al. (2007) Functional LCAT deficiency in human apolipoprotein A-I transgenic, SR-BI knockout mice. J Lipid Res 48:1052-61

Showing the most recent 10 out of 38 publications