CGMP Regulation in the Developing Pulmonary Vasculature

Steinhorn, Robin H.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 2R01HL054705-06A1
• Application #: 6330858
• Study Section: Human Embryology and Development Subcommittee 1 (HED)
• Program Officer: Berberich, Mary Anne
• Project Start: 1995-08-01
• Project End: 2005-07-31
• Budget Start: 2001-08-01
• Budget End: 2002-07-31
• Support Year: 6
• Fiscal Year: 2001
• Total Cost: $319,790

Institution

• Name: Northwestern University at Chicago
• Department: Pediatrics
• Type: Schools of Medicine
• DUNS #: 005436803
• City: Chicago
• State: IL
• Country: United States
• Zip Code: 60611

Publications

Wedgwood, Stephen; Lakshminrusimha, Satyan; Schumacker, Paul T et al. (2015) Hypoxia inducible factor signaling and experimental persistent pulmonary hypertension of the newborn. Front Pharmacol 6:47

Wedgwood, Stephen; Lakshminrusimha, Satyan; Schumacker, Paul T et al. (2015) Cyclic stretch stimulates mitochondrial reactive oxygen species and Nox4 signaling in pulmonary artery smooth muscle cells. Am J Physiol Lung Cell Mol Physiol 309:L196-203

Heilman, Rachel P; Lagoski, Megan B; Lee, Keng Jin et al. (2015) Right ventricular cyclic nucleotide signaling is decreased in hyperoxia-induced pulmonary hypertension in neonatal mice. Am J Physiol Heart Circ Physiol 308:H1575-82

Farrow, Kathryn N; Steinhorn, Robin H (2015) Pulmonary hypertension in premature infants. Sharpening the tools of detection. Am J Respir Crit Care Med 191:12-4

Perez, Marta; Wedgwood, Stephen; Lakshminrusimha, Satyan et al. (2014) Hydrocortisone normalizes phosphodiesterase-5 activity in pulmonary artery smooth muscle cells from lambs with persistent pulmonary hypertension of the newborn. Pulm Circ 4:71-81

Wedgwood, Stephen; Steinhorn, Robin H (2014) Role of reactive oxygen species in neonatal pulmonary vascular disease. Antioxid Redox Signal 21:1926-42

Lee, Keng Jin; Berkelhamer, Sara K; Kim, Gina A et al. (2014) Disrupted pulmonary artery cyclic guanosine monophosphate signaling in mice with hyperoxia-induced pulmonary hypertension. Am J Respir Cell Mol Biol 50:369-78

Ball, Molly K; Waypa, Gregory B; Mungai, Paul T et al. (2014) Regulation of hypoxia-induced pulmonary hypertension by vascular smooth muscle hypoxia-inducible factor-1?. Am J Respir Crit Care Med 189:314-24

Suzuki, Yuichiro J; Steinhorn, Robin H; Gladwin, Mark T (2013) Antioxidant therapy for the treatment of pulmonary hypertension. Antioxid Redox Signal 18:1723-6

Berkelhamer, Sara K; Mestan, Karen K; Steinhorn, Robin H (2013) Pulmonary hypertension in bronchopulmonary dysplasia. Semin Perinatol 37:124-31