Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL055454-01A1
Application #
2234033
Study Section
Pathology A Study Section (PTHA)
Project Start
1996-09-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Willis, Gareth R; Fernandez-Gonzalez, Angeles; Anastas, Jamie et al. (2018) Mesenchymal Stromal Cell Exosomes Ameliorate Experimental Bronchopulmonary Dysplasia and Restore Lung Function through Macrophage Immunomodulation. Am J Respir Crit Care Med 197:104-116
Christou, Helen; Hudalla, Hannes; Michael, Zoe et al. (2018) Impaired Pulmonary Arterial Vasoconstriction and Nitric Oxide-Mediated Relaxation Underlie Severe Pulmonary Hypertension in the Sugen-Hypoxia Rat Model. J Pharmacol Exp Ther 364:258-274
Willis, Gareth R; Mitsialis, S Alex; Kourembanas, Stella (2018) ""Good things come in small packages"": application of exosome-based therapeutics in neonatal lung injury. Pediatr Res 83:298-307
Willis, Gareth R; Kourembanas, Stella; Mitsialis, S Alex (2017) Toward Exosome-Based Therapeutics: Isolation, Heterogeneity, and Fit-for-Purpose Potency. Front Cardiovasc Med 4:63
Mitsialis, S Alex; Kourembanas, Stella (2016) Stem cell-based therapies for the newborn lung and brain: Possibilities and challenges. Semin Perinatol 40:138-51
Kourembanas, Stella (2014) Expanding the pool of stem cell therapy for lung growth and repair. Circulation 129:2091-3
Hale, Andrew; Lee, Changjin; Annis, Sofia et al. (2014) An Argonaute 2 switch regulates circulating miR-210 to coordinate hypoxic adaptation across cells. Biochim Biophys Acta 1843:2528-42
Xiao, Yongguang; Christou, Helen; Liu, Li et al. (2013) Endothelial indoleamine 2,3-dioxygenase protects against development of pulmonary hypertension. Am J Respir Crit Care Med 188:482-91
Anversa, Piero; Perrella, Mark A; Kourembanas, Stella et al. (2012) Regenerative pulmonary medicine: potential and promise, pitfalls and challenges. Eur J Clin Invest 42:900-13
Hansmann, Georg; Fernandez-Gonzalez, Angeles; Aslam, Muhammad et al. (2012) Mesenchymal stem cell-mediated reversal of bronchopulmonary dysplasia and associated pulmonary hypertension. Pulm Circ 2:170-81

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