Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
1R01HL056086-01
Application #
2234699
Study Section
Surgery, Anesthesiology and Trauma Study Section (SAT)
Project Start
1996-05-01
Project End
2000-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost

  Institution

Name
Brigham and Women's Hospital
Department
Type
DUNS #
071723621
City
Boston
State
MA
Country
United States
Zip Code
02115

  Publications

Ozaki, Masayuki; Kang, Yulin; Tan, Ying Siow et al. (2016) Human mannose-binding lectin inhibitor prevents Shiga toxin-induced renal injury. Kidney Int 90:774-82
Pavlov, Vasile I; Tan, Ying S; McClure, Erin E et al. (2015) Human mannose-binding lectin inhibitor prevents myocardial injury and arterial thrombogenesis in a novel animal model. Am J Pathol 185:347-55
Tong, Hua Hua; Lambert, Garrett; Li, Yong Xing et al. (2014) Deletion of the complement C5a receptor alleviates the severity of acute pneumococcal otitis media following influenza A virus infection in mice. PLoS One 9:e95160
Li, Qian; Li, Yong Xing; Douthitt, Kelsey et al. (2012) Role of the alternative and classical complement activation pathway in complement mediated killing against Streptococcus pneumoniae colony opacity variants during acute pneumococcal otitis media in mice. Microbes Infect 14:1308-18
Orsini, Franca; Villa, Pia; Parrella, Sara et al. (2012) Targeting mannose-binding lectin confers long-lasting protection with a surprisingly wide therapeutic window in cerebral ischemia. Circulation 126:1484-94
Stahl, Gregory L; Shernan, Stanton K; Smith, Peter K et al. (2012) Complement activation and cardiac surgery: a novel target for improving outcomes. Anesth Analg 115:759-71
La Bonte, Laura R; Pavlov, Vasile I; Tan, Ying S et al. (2012) Mannose-binding lectin-associated serine protease-1 is a significant contributor to coagulation in a murine model of occlusive thrombosis. J Immunol 188:885-91
Pavlov, Vasile I; Skjoedt, Mikkel-Ole; Siow Tan, Ying et al. (2012) Endogenous and natural complement inhibitor attenuates myocardial injury and arterial thrombogenesis. Circulation 126:2227-35
Pavlov, Vasile I; La Bonte, Laura R; Baldwin, William M et al. (2012) Absence of mannose-binding lectin prevents hyperglycemic cardiovascular complications. Am J Pathol 180:104-12
Burk, Anne-Maud; Martin, Myriam; Flierl, Michael A et al. (2012) Early complementopathy after multiple injuries in humans. Shock 37:348-54

Showing the most recent 10 out of 57 publications