Regulation of Work Capacity in Cardiac Myocytes

McDonald, Kerry S.

Abstract

Funding Agency

• Agency: National Institute of Health (NIH)
• Institute: National Heart, Lung, and Blood Institute (NHLBI)
• Type: Research Project (R01)
• Project #: 7R01HL057852-02
• Application #: 2688210
• Study Section: Cardiovascular and Pulmonary Research A Study Section (CVA)
• Project Start: 1997-09-01
• Project End: 2001-08-31
• Budget Start: 1997-11-01
• Budget End: 1998-08-31
• Support Year: 2
• Fiscal Year: 1997

Institution

• Name: University of Missouri-Columbia
• Department: Physiology
• Type: Schools of Medicine
• DUNS #: 112205955
• City: Columbia
• State: MO
• Country: United States
• Zip Code: 65211

Publications

Hanft, Laurin M; Emter, Craig A; McDonald, Kerry S (2017) Cardiac myofibrillar contractile properties during the progression from hypertension to decompensated heart failure. Am J Physiol Heart Circ Physiol 313:H103-H113

Hanft, Laurin M; Cornell, Timothy D; McDonald, Colin A et al. (2016) Molecule specific effects of PKA-mediated phosphorylation on rat isolated heart and cardiac myofibrillar function. Arch Biochem Biophys 601:22-31

Nance, Michael E; Whitfield, Justin T; Zhu, Yi et al. (2015) Attenuated sarcomere lengthening of the aged murine left ventricle observed using two-photon fluorescence microscopy. Am J Physiol Heart Circ Physiol 309:H918-25

Domeier, Timothy L; Roberts, Cale J; Gibson, Anne K et al. (2014) Dantrolene suppresses spontaneous Ca2+ release without altering excitation-contraction coupling in cardiomyocytes of aged mice. Am J Physiol Heart Circ Physiol 307:H818-29

Hanft, Laurin M; Greaser, Marion L; McDonald, Kerry S (2014) Titin-mediated control of cardiac myofibrillar function. Arch Biochem Biophys 552-553:83-91

Marshall, Kurt D; Muller, Brittany N; Krenz, Maike et al. (2013) Heart failure with preserved ejection fraction: chronic low-intensity interval exercise training preserves myocardial O2 balance and diastolic function. J Appl Physiol (1985) 114:131-47

Hanft, Laurin M; Biesiadecki, Brandon J; McDonald, Kerry S (2013) Length dependence of striated muscle force generation is controlled by phosphorylation of cTnI at serines 23/24. J Physiol 591:4535-47

Hinken, Aaron C; Hanft, Laurin M; Scruggs, Sarah B et al. (2012) Protein kinase C depresses cardiac myocyte power output and attenuates myofilament responses induced by protein kinase A. J Muscle Res Cell Motil 33:439-48

McDonald, Kerry S; Hanft, Laurin M; Domeier, Timothy L et al. (2012) Length and PKA Dependence of Force Generation and Loaded Shortening in Porcine Cardiac Myocytes. Biochem Res Int 2012:371415

Hanft, Laurin M; McDonald, Kerry S (2010) Length dependence of force generation exhibit similarities between rat cardiac myocytes and skeletal muscle fibres. J Physiol 588:2891-903