Agency
National Institute of Health (NIH)
Institute
National Heart, Lung, and Blood Institute (NHLBI)
Type
Research Project (R01)
Project #
5R01HL058687-02
Application #
6041644
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1997-04-01
Project End
2001-03-31
Budget Start
Budget End
Support Year
2
Fiscal Year
1999
Total Cost
Indirect Cost
Name
University of Cincinnati
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Cincinnati
State
OH
Country
United States
Zip Code
45221
Ignacak, M L; Harbaugh, S V; Dayyat, E et al. (2009) Intermittent hypoxia regulates RNA polymerase II in hippocampus and prefrontal cortex. Neuroscience 158:1436-45
Mikhaylova, Olga; Ignacak, Monika L; Barankiewicz, Teresa J et al. (2008) The von Hippel-Lindau tumor suppressor protein and Egl-9-Type proline hydroxylases regulate the large subunit of RNA polymerase II in response to oxidative stress. Mol Cell Biol 28:2701-17
Hui, Anna S; Bauer, Amy L; Striet, Justin B et al. (2006) Calcium signaling stimulates translation of HIF-alpha during hypoxia. FASEB J 20:466-75
Zakrzewska, Adriana; Schnell, Phillip O; Striet, Justin B et al. (2005) Hypoxia-activated metabolic pathway stimulates phosphorylation of p300 and CBP in oxygen-sensitive cells. J Neurochem 94:1288-96
Gozal, Evelyne; Shah, Zahoor A; Pequignot, Jean-Marc et al. (2005) Tyrosine hydroxylase expression and activity in the rat brain: differential regulation after long-term intermittent or sustained hypoxia. J Appl Physiol 99:642-9
Czyzyk-Krzeska, Maria F; Meller, Jaroslaw (2004) von Hippel-Lindau tumor suppressor: not only HIF's executioner. Trends Mol Med 10:146-9
Schnell, Phillip O; Ignacak, Monika L; Bauer, Amy L et al. (2003) Regulation of tyrosine hydroxylase promoter activity by the von Hippel-Lindau tumor suppressor protein and hypoxia-inducible transcription factors. J Neurochem 85:483-91
Hui, Anna S; Striet, Justin B; Gudelsky, Gary et al. (2003) Regulation of catecholamines by sustained and intermittent hypoxia in neuroendocrine cells and sympathetic neurons. Hypertension 42:1130-6
Paulding, Waltke R; Schnell, Phillip O; Bauer, Amy L et al. (2002) Regulation of gene expression for neurotransmitters during adaptation to hypoxia in oxygen-sensitive neuroendocrine cells. Microsc Res Tech 59:178-87
Bauer, Amy L; Paulding, Waltke R; Striet, Justin B et al. (2002) Endogenous von Hippel-Lindau tumor suppressor protein regulates catecholaminergic phenotype in PC12 cells. Cancer Res 62:1682-7

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