The overall goal of the proposed research is to create and test novel targeted intervention techniques for depression (MDD) and generalized anxiety disorder (GAD) based on grant-supported gains in our knowledge about differences in the psychology of failure for individuals with promotion concerns about accomplishment and advancement vs. prevention concerns about security and responsibility. The proposed research will investigate, with both clinical and non-clinical participants, those psychological characteristics of self- regulatory failures that both distinguish between dejection/MDD and anxiety/GAD and permit new and distinct treatments for MDD and GAD. Grant-supported developments in understanding the functioning of regulatory focus orientations (promotion vs. prevention), regulatory fit (when the manner of goal pursuit sustains or disrupts the goal pursuit orientation), and regulatory engagement (when fit increases or non-fit decreases the strength of goal pursuit engagement), provide the foundation for studying the unique characteristics of promotion failure associated with MDD symptomatology vs. prevention failure associated with GAD symptomatology. Project I will investigate differences between promotion and prevention failure, respectively, in the relative importance of comparing one's current self-state to one's past self vs. one's desired future self, and the importance of failing to attain a gain vs. failing to avoid a loss. Project II will develop and test new intervention techniques for treating depression and GAD based on the findings of Project I. Project III will investigate how a promotion failure can generally decrease attraction to possible gains (anhedonia) and a prevention failure can generally increase repulsion to possible losses (generalized anxiety). Project IV will develop and test new intervention techniques for treating MDD and GAD based on the findings of Project III. Project V will use knowledge gained from Projects I &III to improve measures assessing the self-regulatory failures underlying depression and GAD (Project V). The proposed studies will use proven, grant-supported methods for studying the motivational effects of failure for the purpose of translation to clinical interventions.

Public Health Relevance

The proposed studies will investigate the unique psychological characteristics of the promotion failure that is associated with depression and the prevention failure that is associated with generalized anxiety disorder. Translational research will link advances in understanding these differences in the psychology of failure to developing and testing new and targeted techniques for treating depression and generalized anxiety disorder.

Public Health Relevance

The proposed studies will investigate the unique psychological characteristics of the promotion failure that is associated with depression and the prevention failure that is associated with generalized anxiety disorder. Translational research will link advances in understanding these differences in the psychology of failure to developing and testing new and targeted techniques for treating depression and generalized anxiety disorder.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH039429-28
Application #
8065513
Study Section
Social Psychology, Personality and Interpersonal Processes Study Section (SPIP)
Program Officer
Kozak, Michael J
Project Start
1990-01-15
Project End
2013-04-30
Budget Start
2011-05-01
Budget End
2013-04-30
Support Year
28
Fiscal Year
2011
Total Cost
$251,611
Indirect Cost
Name
Columbia University (N.Y.)
Department
Psychology
Type
Other Domestic Higher Education
DUNS #
049179401
City
New York
State
NY
Country
United States
Zip Code
10027
Neacsiu, Andrada D; Luber, Bruce M; Davis, Simon W et al. (2018) On the Concurrent Use of Self-System Therapy and Functional Magnetic Resonance Imaging-Guided Transcranial Magnetic Stimulation as Treatment for Depression. J ECT 34:266-273
Luber, Bruce M; Davis, Simon; Bernhardt, Elisabeth et al. (2017) Using neuroimaging to individualize TMS treatment for depression: Toward a new paradigm for imaging-guided intervention. Neuroimage 148:1-7
Cornwell, James F M; Higgins, E Tory (2016) Eager feelings and vigilant reasons: Regulatory focus differences in judging moral wrongs. J Exp Psychol Gen 145:338-55
Strauman, Timothy J; Socolar, Yvonne; Kwapil, Lori et al. (2015) Microinterventions targeting regulatory focus and regulatory fit selectively reduce dysphoric and anxious mood. Behav Res Ther 72:18-29
Cornwell, James F M; Higgins, E Tory (2014) Locomotion concerns with moral usefulness: When liberals endorse binding moral foundations. J Exp Soc Psychol 50:
Zhang, Shu; Cornwell, James F M; Higgins, E Tory (2014) Repeating the past: prevention focus motivates repetition, even for unethical decisions. Psychol Sci 25:179-87
Higgins, E Tory; Franks, Becca; Pavarini, Dana et al. (2013) Expressed Likelihood as Motivator: Creating Value through Engaging What's Real. J Econ Psychol 38:4-15
Cornwell, James F M; Higgins, E Tory (2013) Morality and its relation to political ideology: the role of promotion and prevention concerns. Pers Soc Psychol Bull 39:1164-72
Higgins, E Tory; Marguc, Janina; Scholer, Abigail A (2012) Value From Adversity: How We Deal With Adversity Matters. J Exp Soc Psychol 48:965-967
Hedberg, Per H; Higgins, E Tory (2011) What Remains on Your Mind After You Are Done?: Flexible Regulation of Knowledge Accessibility. J Exp Soc Psychol 47:882-890

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