The proposed research concerns the follow-up of males initially seen in mental health clinics in 1987, mostly for disruptive behavior disorders at ages 7 to 12. Since that time the participants have been regularly assessed to document the course and outcome of disruptive behavior disorders. The latest assessments were at ages 18 and 19, with the aim of documenting antisocial personality disorder and the infliction of harm. Currently, 36 percent qualify for the diagnosis of antisocial personality disorder. Forty five percent have inflicted moderate to serious injury on other individuals, and 24 percent have attempted suicide. Because violence usually increases during early adulthood, and because the stability of antisocial personality disorder over time is modest, the project proposes to follow up the participants at age 24.
The aims of the proposed research are to test and extend a life-span developmental model of the origins of adult antisocial personality disorder and harm infliction using data on potential risk factors measured from childhood into early adulthood, and to document the relationship between antisocial personality disorder, psychopathy, other personality disorders, and personality traits to identify those individuals who are most at risk to inflict harm and to improve understanding of the adult outcomes of chronic conduct disorder.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
2R01MH042529-14
Application #
6195764
Study Section
Special Emphasis Panel (ZRG1-BBBP-5 (01))
Program Officer
Tuma, Farris K
Project Start
1987-04-01
Project End
2005-07-31
Budget Start
2000-08-16
Budget End
2001-07-31
Support Year
14
Fiscal Year
2000
Total Cost
$270,000
Indirect Cost
Name
University of Pittsburgh
Department
Psychiatry
Type
Schools of Medicine
DUNS #
053785812
City
Pittsburgh
State
PA
Country
United States
Zip Code
15213
White, Helene R; Beardslee, Jordan; Pardini, Dustin (2017) Early predictors of maturing out of marijuana use among young men. Addict Behav 65:56-62
Bechtold, Jordan; Simpson, Theresa; White, Helene R et al. (2015) Chronic adolescent marijuana use as a risk factor for physical and mental health problems in young adult men. Psychol Addict Behav 29:552-63
Pardini, Dustin; Bechtold, Jordan; Loeber, Rolf et al. (2015) Developmental Trajectories of Marijuana Use among Men: Examining Linkages with Criminal Behavior and Psychopathic Features into the Mid-30s. J Res Crime Delinq 52:797-828
Pardini, Dustin; White, Helene R; Xiong, Shuangyan et al. (2015) Unfazed or Dazed and Confused: Does Early Adolescent Marijuana Use Cause Sustained Impairments in Attention and Academic Functioning? J Abnorm Child Psychol 43:1203-17
Burke, Jeffrey D; Rowe, Richard; Boylan, Khrista (2014) Functional outcomes of child and adolescent oppositional defiant disorder symptoms in young adult men. J Child Psychol Psychiatry 55:264-72
Kahn, Rachel E; Byrd, Amy L; Pardini, Dustin A (2013) Callous-unemotional traits robustly predict future criminal offending in young men. Law Hum Behav 37:87-97
Byrd, Amy L; Kahn, Rachel E; Pardini, Dustin A (2013) A Validation of the Inventory of Callous-Unemotional Traits in a Community Sample of Young Adult Males. J Psychopathol Behav Assess 35:
Burke, Jeffrey D (2012) An affective dimension within oppositional defiant disorder symptoms among boys: personality and psychopathology outcomes into early adulthood. J Child Psychol Psychiatry 53:1176-83
Keijsers, Loes; Loeber, Rolf; Branje, Susan et al. (2012) Parent-child relationships of boys in different offending trajectories: a developmental perspective. J Child Psychol Psychiatry 53:1222-32
Pardini, Dustin A; Loeber, Rolf; Farrington, David P et al. (2012) Identifying direct protective factors for nonviolence. Am J Prev Med 43:S28-40

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