Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH045045-10
Application #
2885014
Study Section
Project Start
1991-05-01
Project End
2001-04-30
Budget Start
1998-05-01
Budget End
1999-04-30
Support Year
10
Fiscal Year
1998
Total Cost
Indirect Cost
Milligan, Erin D; Maier, Steven F; Watkins, Linda R (2004) Sciatic inflammatory neuropathy in the rat: surgical procedures, induction of inflammation, and behavioral testing. Methods Mol Med 99:67-89
Watkins, Linda R; Milligan, Erin D; Maier, Steven F (2003) Glial proinflammatory cytokines mediate exaggerated pain states: implications for clinical pain. Adv Exp Med Biol 521:1-21
O'Connor, Kevin A; Hansen, Michael K; Rachal Pugh, C et al. (2003) Further characterization of high mobility group box 1 (HMGB1) as a proinflammatory cytokine: central nervous system effects. Cytokine 24:254-65
O'Connor, Kevin A; Johnson, John D; Hansen, Michael K et al. (2003) Peripheral and central proinflammatory cytokine response to a severe acute stressor. Brain Res 991:123-32
O'Connor, K A; Johnson, J D; Hammack, S E et al. (2003) Inescapable shock induces resistance to the effects of dexamethasone. Psychoneuroendocrinology 28:481-500
Milligan, Erin D; Twining, Carin; Chacur, Marucia et al. (2003) Spinal glia and proinflammatory cytokines mediate mirror-image neuropathic pain in rats. J Neurosci 23:1026-40
Goehler, L E; Gaykema, R P; Hansen, M K et al. (2001) Staphylococcal enterotoxin B induces fever, brain c-Fos expression, and serum corticosterone in rats. Am J Physiol Regul Integr Comp Physiol 280:R1434-9
Hansen, M K; O'Connor, K A; Goehler, L E et al. (2001) The contribution of the vagus nerve in interleukin-1beta-induced fever is dependent on dose. Am J Physiol Regul Integr Comp Physiol 280:R929-34
Watkins, L R; Milligan, E D; Maier, S F (2001) Glial activation: a driving force for pathological pain. Trends Neurosci 24:450-5
Gazda, L S; Milligan, E D; Hansen, M K et al. (2001) Sciatic inflammatory neuritis (SIN): behavioral allodynia is paralleled by peri-sciatic proinflammatory cytokine and superoxide production. J Peripher Nerv Syst 6:111-29

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