Although boys with attention-deficit hyperactivity disorder (ADHD) are at risk for persistent symptomatology and negative outcomes in adolescence and adulthood, there is almost no information on the prospective follow-up of girls with ADHD. Furthermore, data on the developmental course of the Inattentive type of ADHD (which is of particular salience for females) are almost nonexistent. The key purpose of the proposed continuation is to follow prospectively a diverse and well-characterized sample of preadolescent girls with ADHD plus a matched comparison group. The PI has gathered a comprehensive database on this sample, which includes state-of-the-art clinical assessment plus multi-domain/multi-informant information from naturalistic research settings. Subjects are on 140 ethnically diverse girls with ADHD (both Combined and Inattentive types) and 88 comparison girls, all of whom were 6-12 years of age during baseline assessment. The initial database spans key domains (ADHD symptomatology; disruptive and internalizing comorbidity; functional impairment in home, school, and peer settings; cognitive and neuropsychological performance), reflects unmedicated behavior, and features ecologically valid observational and peer sociometric data collected during summer research programs. The proposed research incorporates comprehensive, 4-year, prospective follow-up (at ages 11-16.5 years), across multiple domains of symptoms, impairment, and competence. A key aim is to describe change and stability across the period from childhood to adolescence in girls with ADHD. Another is to build predictive and explanatory models that test the salience of behavioral, cognitive, and environmental factors in explaining persistence and desistance from ADHD-related symptomatology and comorbidity. A third features the testing of risk/resiliency models in explaining competencies at follow up. Featured are (a) contrasts of Combined- vs. Inattentive-type ADHD and (b) person-centered approaches to appraising developmental mechanisms. Overall, prospective follow-up is necessary to evaluate processes and mechanisms underlying both stability and discontinuity in the understudied population of females with ADHD. The proposed research features a large and well-characterized sample plus conceptually sound and developmentally based assessment procedures.

National Institute of Health (NIH)
National Institute of Mental Health (NIMH)
Research Project (R01)
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Special Emphasis Panel (ZRG1-BBBP-6 (01))
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Rumsey, Judith M
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University of California Berkeley
Other Health Professions
Other Domestic Higher Education
United States
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Ahmad, Shaikh I; Hinshaw, Stephen P (2017) Attention-Deficit/Hyperactivity Disorder, Trait Impulsivity, and Externalizing Behavior in a Longitudinal Sample. J Abnorm Child Psychol 45:1077-1089
Gordon, Chanelle T; Hinshaw, Stephen P (2017) Parenting Stress and Youth Symptoms among Girls with and without ADHD. Parent Sci Pract 17:11-29
Gordon, Chanelle T; Hinshaw, Stephen P (2017) Parenting Stress as a Mediator Between Childhood ADHD and Early Adult Female Outcomes. J Clin Child Adolesc Psychol 46:588-599
Owens, Elizabeth B; Zalecki, Christine; Gillette, Peter et al. (2017) Girls with childhood ADHD as adults: Cross-domain outcomes by diagnostic persistence. J Consult Clin Psychol 85:723-736
Lundervold, Astri J; Meza, Jocelyn I; Hysing, Mari et al. (2017) Parent Rated Symptoms of Inattention in Childhood Predict High School Academic Achievement Across Two Culturally and Diagnostically Diverse Samples. Front Psychol 8:1436
Guendelman, Maya D; Owens, Elizabeth B; Galán, Chardee et al. (2016) Early-adult correlates of maltreatment in girls with attention-deficit/hyperactivity disorder: Increased risk for internalizing symptoms and suicidality. Dev Psychopathol 28:1-14
Owens, Elizabeth B; Hinshaw, Stephen P (2016) Childhood conduct problems and young adult outcomes among women with childhood attention-deficit/hyperactivity disorder (ADHD). J Abnorm Psychol 125:220-232
Guendelman, Maya D; Ahmad, Shaikh; Meza, Jocelyn I et al. (2016) Childhood Attention-Deficit/Hyperactivity Disorder Predicts Intimate Partner Victimization in Young Women. J Abnorm Child Psychol 44:155-66
Gard, Arianna M; Owens, Elizabeth B; Hinshaw, Stephen P (2016) Prenatal Smoke Exposure Predicts Hyperactive/Impulsive but Not Inattentive ADHD Symptoms in Adolescent and Young Adult Girls. Infant Child Dev 25:339-351
Meza, Jocelyn I; Owens, Elizabeth B; Hinshaw, Stephen P (2016) Response Inhibition, Peer Preference and Victimization, and Self-Harm: Longitudinal Associations in Young Adult Women with and without ADHD. J Abnorm Child Psychol 44:323-34

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