Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
1R01MH051290-01A1
Application #
2250536
Study Section
Molecular, Cellular, and Developmental Neurobiology Review Committee (MCDN)
Project Start
1994-08-01
Project End
1997-07-31
Budget Start
1994-08-01
Budget End
1995-07-31
Support Year
1
Fiscal Year
1994
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Li, Suyan; Uno, Yota; Rudolph, Uwe et al. (2018) Astrocytes in primary cultures express serine racemase, synthesize d-serine and acquire A1 reactive astrocyte features. Biochem Pharmacol 151:245-251
Balu, Darrick T; Presti, Kendall Taylor; Huang, Cathy C Y et al. (2018) Serine Racemase and D-serine in the Amygdala Are Dynamically Involved in Fear Learning. Biol Psychiatry 83:273-283
Noh, Haneul; Shao, Zhicheng; Coyle, Joseph T et al. (2017) Modeling schizophrenia pathogenesis using patient-derived induced pluripotent stem cells (iPSCs). Biochim Biophys Acta Mol Basis Dis 1863:2382-2387
Coyle, Joseph T; Konopaske, Glenn (2016) Glutamatergic Dysfunction in Schizophrenia Evaluated With Magnetic Resonance Spectroscopy. JAMA Psychiatry 73:649-50
Coyle, J T (2016) My Life in Clinical Neuroscience: The Beginning. Adv Pharmacol 76:1-12
Wolosker, Herman; Balu, Darrick T; Coyle, Joseph T (2016) The Rise and Fall of the d-Serine-Mediated Gliotransmission Hypothesis. Trends Neurosci 39:712-721
Basu, Alo C; Puhl, Matthew D; Coyle, Joseph T (2016) Endogenous co-agonists of the NMDA receptor modulate contextual fear in trace conditioning. Neurobiol Learn Mem 136:244-250
Balu, Darrick T; Li, Yan; Takagi, Shunsuke et al. (2016) An mGlu5-Positive Allosteric Modulator Rescues the Neuroplasticity Deficits in a Genetic Model of NMDA Receptor Hypofunction in Schizophrenia. Neuropsychopharmacology 41:2052-61
Kangas, Brian D; Bergman, Jack; Coyle, Joseph T (2016) Touchscreen assays of learning, response inhibition, and motivation in the marmoset (Callithrix jacchus). Anim Cogn 19:673-7
Coyle, Joseph T; Balu, Darrick T; Puhl, Matthew D et al. (2016) History of the Concept of Disconnectivity in Schizophrenia. Harv Rev Psychiatry 24:80-6

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