The overall goal is to evaluate a program of primary prevention in young children at high risk for developing conduct problems and later antisocial behavior. This investigation is prompted by 1) the serious nature of childhood conduct problems; 2) their poor long- term prognosis; 3) their resistance to treatment; 4) the absence of preventive interventions studies for very young high-risk children; and 5) the paucity of intervention programs tailored to inner-city families. The timing for prevention experiments is ideal, since their design can now rest on rational bases derived from our current knowledge about risk factors for conduct problems and antisocial behavior. A randomized controlled clinical trial of a multisystemic, intensive intervention for families of high-risk preschoolers is proposed. Ninety-six inner-city preschoolers who have older siblings with court-documented histories of antisocial behavior will be randomly assigned to a year-long family-based intervention or to a no contact control group. The intervention will consist o clinic and home-based parenting skills training. Immediate and long-term (1 year) outcome of children receiving intervention and controls will be compared. Outcome variables, including parenting practices, child conduct problems and child social competence, will be assessed with blind observations in multiple settings, as well as by parent and teacher ratings, and structured diagnostic interviews. This study is unique in that 1) the preventive intervention is truly primary-it targets preschoolers who are at high risk for developing conduct problems and later antisocial behaviors but who do not yet display these behaviors; 2) it assesses the efficacy of an intensive, family- based preventive intervention for reducing a key risk factor for conduct problems-inadequate parenting practices; 3) the intervention is tailored to inner-city families; 4) recruitment, assessment and intervention procedures have been tested for feasibility; and 5) the prevention program has been manualized.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
7R01MH055188-03
Application #
2873910
Study Section
Child/Adolescent Risk and Prevention Review Committee (CAPR)
Project Start
1997-03-01
Project End
2002-02-28
Budget Start
1998-08-01
Budget End
1999-02-28
Support Year
3
Fiscal Year
1998
Total Cost
Indirect Cost
Name
New York University
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
New York
State
NY
Country
United States
Zip Code
10016
Theise, Rachelle; Huang, Keng-Yen; Kamboukos, Dimitra et al. (2014) Moderators of intervention effects on parenting practices in a randomized controlled trial in early childhood. J Clin Child Adolesc Psychol 43:501-9
Brotman, Laurie Miller; Calzada, Esther; Huang, Keng-Yen et al. (2011) Promoting effective parenting practices and preventing child behavior problems in school among ethnically diverse families from underserved, urban communities. Child Dev 82:258-76
O'Neal, Colleen R; Brotman, Laurie Miller; Huang, Keng-Yen et al. (2010) Understanding relations among early family environment, cortisol response, and child aggression via a prevention experiment. Child Dev 81:290-305
Brotman, Laurie Miller; Gouley, Kathleen Kiely; Huang, Keng-Yen et al. (2007) Effects of a psychosocial family-based preventive intervention on cortisol response to a social challenge in preschoolers at high risk for antisocial behavior. Arch Gen Psychiatry 64:1172-9
Brotman, Laurie Miller; Gouley, Kathleen Kiely; Chesir-Teran, Daniel et al. (2005) Prevention for preschoolers at high risk for conduct problems: immediate outcomes on parenting practices and child social competence. J Clin Child Adolesc Psychol 34:724-34
Brotman, Laurie Miller; Dawson-McClure, Spring; Gouley, Kathleen Kiely et al. (2005) Older siblings benefit from a family-based preventive intervention for preschoolers at risk for conduct problems. J Fam Psychol 19:581-91