This proposal seeks to extend through late adolescence and into early adulthood an examination of normal and pathogenic development and the impact of two universal first grade preventive interventions on the distal targets of substance abuse, antisocial behavior and anxious and depressive symptoms and disorders. We will build on the scientific value of an existing, prospective, developmental epidemiologica) data base involving a defined population of urban school children, whose psychological well-being and social adaptational status have been assessed periodically from 1993 through 2001, grades 1 -8 (or ages 6-13). Funds are available from NIMH and NIDA through the Spring of 2002 for a ninth grade assessment that includes youth, parent, teacher, and school mental health professional reports. Funding from NIDA is also available for youth, teacher, and school mental health professional assessments in 10th grade. In this proposal, we are requesting funds (1) to expand our 10th grade assessments to include a parent interview, (2) to continue obtaining youth, parent, teacher and mental health professional reports in grades 11 & 12, and (3) to gather youth and parent reports one year after high school. The study population consists of the entire cohort of children (N = 678) who began first grade in the fall of 1993 in 9 elementary schools in predominantly low to lower middle income areas in Baltimore. Within each of the 9 schools, children and their teachers were randomly assigned to either a standard classroom or to a classroom featuring one of two universal preventive interventions. Each intervention specifically targeted two confirmed antecedents of later antisocial behavior, substance use and anxiety and depression: 1) aggressive and shy behaviors, and 2) poor school achievement. The Classroom-Centered intervention (CC) sought to reduce the early risk behaviors of poor achievement and aggressive and shy behaviors through the enhancement of classroom curricula and teacher instructional and behavior management practices, whereas the Family-School Partnership intervention (FSP) focused on parent discipline practices and parent-school communication. Follow-up through age l8 will allow us to assess the impact of the interventions on the risk for substance, mood, and conduct problems and disorders in adolescence and early adulthood, and the corresponding need for, use, and associated costs of mental health and special education services.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
5R01MH057005-10
Application #
7248557
Study Section
Risk, Prevention and Health Behavior Integrated Review Group (RPHB)
Program Officer
Goldstein, Amy B
Project Start
1998-07-01
Project End
2009-06-30
Budget Start
2007-07-01
Budget End
2009-06-30
Support Year
10
Fiscal Year
2007
Total Cost
$253,226
Indirect Cost
Name
Johns Hopkins University
Department
Type
Schools of Public Health
DUNS #
001910777
City
Baltimore
State
MD
Country
United States
Zip Code
21218
Musci, Rashelle J; Fairman, Brian; Masyn, Katherine E et al. (2018) Polygenic Score × Intervention Moderation: an Application of Discrete-Time Survival Analysis to Model the Timing of First Marijuana Use Among Urban Youth. Prev Sci 19:6-14
Tache, Rachel M; Lambert, Sharon F; Ganiban, Jody M et al. (2018) Temperament Moderators of Prospective Associations Between Community Violence Exposure and Urban African American Adolescents' Aggressive Behavior. Child Psychiatry Hum Dev 49:709-717
Musci, Rashelle J; Bettencourt, Amie F; Sisto, Danielle et al. (2018) Evaluating the genetic susceptibility to peer reported bullying behaviors. Psychiatry Res 263:193-198
Green, Kerry M; Musci, Rashelle J; Matson, Pamela A et al. (2017) Developmental Patterns of Adolescent Marijuana and Alcohol Use and Their Joint Association with Sexual Risk Behavior and Outcomes in Young Adulthood. J Urban Health 94:115-124
Green, Kerry M; Musci, Rashelle J; Johnson, Renee M et al. (2016) Outcomes associated with adolescent marijuana and alcohol use among urban young adults: A prospective study. Addict Behav 53:155-60
English, Devin; Lambert, Sharon F; Ialongo, Nicholas S (2016) Adding to the Education Debt: Depressive Symptoms Mediate the Association between Racial Discrimination and Academic Performance in African Americans. J Sch Psychol 57:29-40
Lopez-Tamayo, Roberto; LaVome Robinson, W; Lambert, Sharon F et al. (2016) Parental Monitoring, Association with Externalized Behavior, and Academic Outcomes in Urban African-American Youth: A Moderated Mediation Analysis. Am J Community Psychol 57:366-79
Musci, Rashelle J; Masyn, Katherine E; Benke, Kelly et al. (2016) The effects of the interplay of genetics and early environmental risk on the course of internalizing symptoms from late childhood through adolescence. Dev Psychopathol 28:225-37
Musci, Rashelle J; Masyn, Katherine E; Uhl, George et al. (2015) Polygenic score × intervention moderation: an application of discrete-time survival analysis to modeling the timing of first tobacco use among urban youth. Dev Psychopathol 27:111-22
Reboussin, Beth A; Ialongo, Nicholas S; Green, Kerry M (2015) Influences of behavior and academic problems at school entry on marijuana use transitions during adolescence in an African-American sample. Addict Behav 41:51-7

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