description): The principal objectives of the proposed study are to 1) assess the acceptability of female- controlled sexual barrier methods in ethnically diverse populations in the developed and developing world, 2) develop and test the efficacy of culturally sensitive interventions using cognitive/behavioral strategies and experiential training techniques to facilitate negotiation skills and coping strategies to increase and maintain sexual barrier use and 3) identify factors that influence the initiation and maintenance of microbicide use to reduce the transmission of HIV/STDs in the target populations. Low income women of color living with HIV/AIDS are among the most neglected and understudied populations affected by the AIDS epidemic. The sites selected for the proposed research grant reflects two major epicenters of HIV incidence in women in the developed and developing worlds: in the United States, Miami, Florida, and in Africa, Lusaka, Zambia. Florida ranks third in the United States for newly reported AIDS cases; Miami-Dade County has the highest incidence of HIV/AIDS in Florida. Among minority women living with HIV in Florida, 59% are African American, 25% are Hispanic, and 16% are Haitian. Approximately 25% of Lusaka's 2 million inhabitants are HIV seropositive; this figure is projected to double by 2005. To accomplish the above objectives, the proposed two-site clinical trial will randomize a total of 900 ethnically diverse (African American, Hispanic, Haitian, Caucasian, Zambian) women living with HIV/AIDS (Miami: n = 450; Lusaka: n = 450) into 1) a group cognitive/behavioral safer sex skills training experimental condition, 2) an individual """"""""enhanced usual care"""""""" comparison condition or 3) a """"""""usual care"""""""" control condition. Both experimental group and comparison individual conditions will receive a manualized three session program devoted to safer sex and female controlled barrier methods based upon the New York Hierarchy of safer sexual practices. In addition to baseline assessment and session evaluations, long term follow-up assessments will be carried out at 6 and 12 months.

Agency
National Institute of Health (NIH)
Institute
National Institute of Mental Health (NIMH)
Type
Research Project (R01)
Project #
3R01MH063630-03S1
Application #
6668190
Study Section
Special Emphasis Panel (ZHD1 (05))
Program Officer
Gordon, Christopher M
Project Start
2000-09-30
Project End
2005-08-31
Budget Start
2002-09-01
Budget End
2003-08-31
Support Year
3
Fiscal Year
2002
Total Cost
$53,164
Indirect Cost
Name
University of Miami School of Medicine
Department
Psychiatry
Type
Schools of Medicine
DUNS #
City
Miami
State
FL
Country
United States
Zip Code
33146
Jones, Deborah; Weiss, Stephen; Chitalu, Ndashi (2015) HIV Prevention in Resource Limited Settings: A Case Study of Challenges and Opportunities for Implementation. Int J Behav Med 22:384-92
Jones, Deborah; Kashy, Deborah; Chitalu, Ndashi et al. (2014) Risk reduction among HIV-seroconcordant and -discordant couples: the Zambia NOW2 intervention. AIDS Patient Care STDS 28:433-41
Jones, Deborah; Bagga, Rashmi; Nehra, Ritu et al. (2013) Reducing sexual risk behavior among high-risk couples in Northern India. Int J Behav Med 20:344-54
Jones, Deborah; Kashy, Deborah; Villar-Loubet, Olga et al. (2013) Enhancing acceptability and use of sexual barrier products among HIV concordant and discordant couples. AIDS Behav 17:2185-93
Jones, Deborah L; Kashy, Deborah; Villar-Loubet, Olga M et al. (2013) The impact of substance use, sexual trauma, and intimate partner violence on sexual risk intervention outcomes in couples: a randomized trial. Ann Behav Med 45:318-28
Weiss, Stephen M; Jones, Deborah L; Lopez, Maria et al. (2011) The many faces of translational research: a tale of two studies. Transl Behav Med 1:327-330
Villar-Loubet, Olga M; Vamos, Szonja; Jones, Deborah L et al. (2011) A Cultural Perspective on Sexual Health: HIV Positive and Negative Monolingual Hispanic Women in South Florida. Hisp Health Care Int 9:82-90
Villar-Loubet, Olga; Jones, Deborah; Waldrop-Valverde, Drenna et al. (2011) Sexual barrier acceptability among multiethnic HIV-positive and at-risk women. J Womens Health (Larchmt) 20:365-73
Lopez, Eliot J; Jones, Deborah L; Villar-Loubet, Olga M et al. (2010) Violence, coping, and consistent medication adherence in HIV-positive couples. AIDS Educ Prev 22:61-8
Jones, Deborah L; Weiss, Stephen M; Chitalu, Nadashi et al. (2008) Acceptability of microbicidal surrogates among Zambian women. Sex Transm Dis 35:147-53

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