Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS012636-22
Application #
2262460
Study Section
Respiratory and Applied Physiology Study Section (RAP)
Project Start
1978-07-01
Project End
1998-06-30
Budget Start
1996-07-01
Budget End
1997-06-30
Support Year
22
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Utah
Department
Physiology
Type
Schools of Medicine
DUNS #
City
Salt Lake City
State
UT
Country
United States
Zip Code
84112
Wilkinson, Katherine A; Huey, Kimberly; Dinger, Bruce et al. (2010) Chronic hypoxia increases the gain of the hypoxic ventilatory response by a mechanism in the central nervous system. J Appl Physiol (1985) 109:424-30
He, L; Liu, X; Chen, J et al. (2010) Modulation of chronic hypoxia-induced chemoreceptor hypersensitivity by NADPH oxidase subunits in rat carotid body. J Appl Physiol (1985) 108:1304-10
Liu, X; He, L; Stensaas, L et al. (2009) Adaptation to chronic hypoxia involves immune cell invasion and increased expression of inflammatory cytokines in rat carotid body. Am J Physiol Lung Cell Mol Physiol 296:L158-66
Dinger, B; He, L; Chen, J et al. (2007) The role of NADPH oxidase in carotid body arterial chemoreceptors. Respir Physiol Neurobiol 157:45-54
He, L; Chen, J; Liu, X et al. (2007) Enhanced nitric oxide-mediated chemoreceptor inhibition and altered cyclic GMP signaling in rat carotid body following chronic hypoxia. Am J Physiol Lung Cell Mol Physiol 293:L1463-8
Chen, Jia; He, Liang; Liu, Xuemei et al. (2007) Effect of the endothelin receptor antagonist bosentan on chronic hypoxia-induced morphological and physiological changes in rat carotid body. Am J Physiol Lung Cell Mol Physiol 292:L1257-62
He, L; Dinger, B; Gonzalez, C et al. (2006) Function of NADPH oxidase and signaling by reactive oxygen species in rat carotid body type I cells. Adv Exp Med Biol 580:155-60; discussion 351-9
He, L; Chen, J; Dinger, B et al. (2006) Effect of chronic hypoxia on purinergic synaptic transmission in rat carotid body. J Appl Physiol 100:157-62
He, L; Dinger, B; Sanders, K et al. (2005) Effect of p47phox gene deletion on ROS production and oxygen sensing in mouse carotid body chemoreceptor cells. Am J Physiol Lung Cell Mol Physiol 289:L916-24
He, L; Dinger, B; Fidone, S (2005) Effect of chronic hypoxia on cholinergic chemotransmission in rat carotid body. J Appl Physiol 98:614-9

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