Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS014610-15S2
Application #
2262661
Study Section
Biopsychology Study Section (BPO)
Project Start
1983-02-01
Project End
1996-09-30
Budget Start
1994-04-01
Budget End
1995-03-31
Support Year
15
Fiscal Year
1994
Total Cost
Indirect Cost
Name
University of California Los Angeles
Department
Type
Other Domestic Higher Education
DUNS #
119132785
City
Los Angeles
State
CA
Country
United States
Zip Code
90095
Shan, Ling; Dauvilliers, Yves; Siegel, Jerome M (2015) Interactions of the histamine and hypocretin systems in CNS disorders. Nat Rev Neurol 11:401-13
Ramanathan, Lalini; Siegel, Jerome M (2014) Gender differences between hypocretin/orexin knockout and wild type mice: age, body weight, body composition, metabolic markers, leptin and insulin resistance. J Neurochem 131:615-24
John, Joshi; Kodama, Tohru; Siegel, Jerome M (2014) Caffeine promotes glutamate and histamine release in the posterior hypothalamus. Am J Physiol Regul Integr Comp Physiol 307:R704-10
Hsieh, Kung-Chiao; Nguyen, Darian; Siegel, Jerome M et al. (2013) New pathways and data on rapid eye movement sleep behaviour disorder in a rat model. Sleep Med 14:719-28
Blouin, Ashley M; Fried, Itzhak; Wilson, Charles L et al. (2013) Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction. Nat Commun 4:1547
John, Joshi; Thannickal, Thomas C; McGregor, Ronald et al. (2013) Greatly increased numbers of histamine cells in human narcolepsy with cataplexy. Ann Neurol 74:786-93
Scammell, T E; Matheson, J K; Honda, M et al. (2012) Coexistence of narcolepsy and Alzheimer's disease. Neurobiol Aging 33:1318-9
Siegel, Jerome M (2011) REM sleep: a biological and psychological paradox. Sleep Med Rev 15:139-42
McGregor, Ronald; Wu, Ming-Fung; Barber, Grace et al. (2011) Highly specific role of hypocretin (orexin) neurons: differential activation as a function of diurnal phase, operant reinforcement versus operant avoidance and light level. J Neurosci 31:15455-67
Wu, Ming-Fung; Nienhuis, Robert; Maidment, Nigel et al. (2011) Role of the hypocretin (orexin) receptor 2 (Hcrt-r2) in the regulation of hypocretin level and cataplexy. J Neurosci 31:6305-10

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