Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS015662-17
Application #
2262867
Study Section
Neurology C Study Section (NEUC)
Project Start
1979-07-01
Project End
2000-01-31
Budget Start
1996-03-01
Budget End
1997-01-31
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Maryland Baltimore
Department
Pathology
Type
Schools of Medicine
DUNS #
003255213
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Weerth, Susanna H; Rus, Horea; Shin, Moon L et al. (2003) Complement C5 in experimental autoimmune encephalomyelitis (EAE) facilitates remyelination and prevents gliosis. Am J Pathol 163:1069-80
Niculescu, Teodora; Weerth, Susanna; Soane, Lucian et al. (2003) Effects of membrane attack complex of complement on apoptosis in experimental autoimmune encephalomyelitis. Ann N Y Acad Sci 1010:530-3
Rus, H G; Niculescu, F I; Shin, M L (2001) Role of the C5b-9 complement complex in cell cycle and apoptosis. Immunol Rev 180:49-55
Soane, L; Cho, H J; Niculescu, F et al. (2001) C5b-9 terminal complement complex protects oligodendrocytes from death by regulating Bad through phosphatidylinositol 3-kinase/Akt pathway. J Immunol 167:2305-11
Niculescu, F; Soane, L; Badea, T et al. (1999) Tyrosine phosphorylation and activation of Janus kinase 1 and STAT3 by sublytic C5b-9 complement complex in aortic endothelial cells. Immunopharmacology 42:187-93
Soane, L; Rus, H; Niculescu, F et al. (1999) Inhibition of oligodendrocyte apoptosis by sublytic C5b-9 is associated with enhanced synthesis of bcl-2 and mediated by inhibition of caspase-3 activation. J Immunol 163:6132-8
Noe, K H; Cenciarelli, C; Moyer, S A et al. (1999) Requirements for measles virus induction of RANTES chemokine in human astrocytoma-derived U373 cells. J Virol 73:3117-24
Cheng, G; Nazar, A S; Shin, H S et al. (1998) IP-10 gene transcription by virus in astrocytes requires cooperation of ISRE with adjacent kappaB site but not IRF-1 or viral transcription. J Interferon Cytokine Res 18:987-97
Vanguri, P; Cho, S Y; Chi, C M (1996) Role of muIP-10 in interferon-gamma induction of Ia in rat astrocytes. Mol Immunol 33:1079-87
Kim, Y U; Rus, H G; Fisher, S N et al. (1996) Binding of a protein to an AU-rich domain of tumour necrosis factor alpha mRNA as a 35 kDa complex and its regulation in primary rat astrocytes. Biochem J 316 ( Pt 2):455-60

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