Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS015751-17
Application #
2262894
Study Section
Physiology Study Section (PHY)
Project Start
1979-12-01
Project End
1998-11-30
Budget Start
1995-12-01
Budget End
1996-11-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Pharmacology
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Gamal El-Din, Tamer M; Lenaeus, Michael J; Catterall, William A (2018) Structural and Functional Analysis of Sodium Channels Viewed from an Evolutionary Perspective. Handb Exp Pharmacol 246:53-72
Jiang, Daohua; Gamal El-Din, Tamer M; Ing, Christopher et al. (2018) Structural basis for gating pore current in periodic paralysis. Nature 557:590-594
Lenaeus, Michael J; Gamal El-Din, Tamer M; Ing, Christopher et al. (2017) Structures of closed and open states of a voltage-gated sodium channel. Proc Natl Acad Sci U S A 114:E3051-E3060
Alexander, Stephen Ph; Kelly, Eamonn; Marrion, Neil V et al. (2017) THE CONCISE GUIDE TO PHARMACOLOGY 2017/18: Overview. Br J Pharmacol 174 Suppl 1:S1-S16
Catterall, William A (2017) Forty Years of Sodium Channels: Structure, Function, Pharmacology, and Epilepsy. Neurochem Res 42:2495-2504
Catterall, William A; Wisedchaisri, Goragot; Zheng, Ning (2017) The chemical basis for electrical signaling. Nat Chem Biol 13:455-463
Southan, Christopher; Sharman, Joanna L; Benson, Helen E et al. (2016) The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. Nucleic Acids Res 44:D1054-68
Catterall, William A (2015) Finding Channels. J Biol Chem 290:28357-73
Catterall, William A; Swanson, Teresa M (2015) Structural Basis for Pharmacology of Voltage-Gated Sodium and Calcium Channels. Mol Pharmacol 88:141-50
Chen-Izu, Ye; Shaw, Robin M; Pitt, Geoffrey S et al. (2015) Na+ channel function, regulation, structure, trafficking and sequestration. J Physiol 593:1347-60

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