Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS016792-15
Application #
2263085
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1982-04-01
Project End
1999-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
15
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Washington
Department
Physiology
Type
Schools of Medicine
DUNS #
135646524
City
Seattle
State
WA
Country
United States
Zip Code
98195
Oakley, J C; Schwindt, P C; Crill, W E (2001) Dendritic calcium spikes in layer 5 pyramidal neurons amplify and limit transmission of ligand-gated dendritic current to soma. J Neurophysiol 86:514-27
Oakley, J C; Schwindt, P C; Crill, W E (2001) Initiation and propagation of regenerative Ca(2+)-dependent potentials in dendrites of layer 5 pyramidal neurons. J Neurophysiol 86:503-13
Schwindt, P; Crill, W (1999) Mechanisms underlying burst and regular spiking evoked by dendritic depolarization in layer 5 cortical pyramidal neurons. J Neurophysiol 81:1341-54
Crill, W E; Schwindt, P C (1999) Membrane properties and epilepsy. Adv Neurol 79:493-8
Lampl, I; Schwindt, P; Crill, W (1998) Reduction of cortical pyramidal neuron excitability by the action of phenytoin on persistent Na+ current. J Pharmacol Exp Ther 284:228-37
Schwindt, P C; Crill, W E (1998) Synaptically evoked dendritic action potentials in rat neocortical pyramidal neurons. J Neurophysiol 79:2432-46
Mittmann, T; Linton, S M; Schwindt, P et al. (1997) Evidence for persistent Na+ current in apical dendrites of rat neocortical neurons from imaging of Na+-sensitive dye. J Neurophysiol 78:1188-92
Schwindt, P; O'Brien, J A; Crill, W (1997) Quantitative analysis of firing properties of pyramidal neurons from layer 5 of rat sensorimotor cortex. J Neurophysiol 77:2484-98
Widener, G L; Cheney, P D (1997) Effects on muscle activity from microstimuli applied to somatosensory and motor cortex during voluntary movement in the monkey. J Neurophysiol 77:2446-65
Schwindt, P C; Crill, W E (1997) Local and propagated dendritic action potentials evoked by glutamate iontophoresis on rat neocortical pyramidal neurons. J Neurophysiol 77:2466-83

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