Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
2R01NS018458-17
Application #
2263420
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1981-09-01
Project End
2001-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
17
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Harvard University
Department
Biology
Type
Schools of Medicine
DUNS #
082359691
City
Boston
State
MA
Country
United States
Zip Code
02115
Bianchetta, Michael J; Betensky, Rebecca A; Cohen, Jonathan B (2005) Cell-surface MuSK self-association: a crucial role for the putative signal sequence. Biochemistry 44:16229-38
Trinidad, Jonathan C; Cohen, Jonathan B (2004) Neuregulin inhibits acetylcholine receptor aggregation in myotubes. J Biol Chem 279:31622-8
Ford, Byron D; Liu, Yun; Mann, Mary Anne et al. (2003) Neuregulin-1 suppresses muscarinic receptor expression and acetylcholine-activated muscarinic K+ channels in cardiac myocytes. Biochem Biophys Res Commun 308:23-8
Ford, Byron D; Han, Bomie; Fischbach, Gerald D (2003) Differentiation-dependent regulation of skeletal myogenesis by neuregulin-1. Biochem Biophys Res Commun 306:276-81
Loeb, Jeffrey A; Hmadcha, Abdelkrim; Fischbach, Gerald D et al. (2002) Neuregulin expression at neuromuscular synapses is modulated by synaptic activity and neurotrophic factors. J Neurosci 22:2206-14
Ramarao, M K; Bianchetta, M J; Lanken, J et al. (2001) Role of rapsyn tetratricopeptide repeat and coiled-coil domains in self-association and nicotinic acetylcholine receptor clustering. J Biol Chem 276:7475-83
Viehover, A; Miller, R H; Park, S K et al. (2001) Neuregulin: an oligodendrocyte growth factor absent in active multiple sclerosis lesions. Dev Neurosci 23:377-86
Bartoli, M; Ramarao, M K; Cohen, J B (2001) Interactions of the rapsyn RING-H2 domain with dystroglycan. J Biol Chem 276:24911-7
Vartanian, T; Goodearl, A; Lefebvre, S et al. (2000) Neuregulin induces the rapid association of focal adhesion kinase with the erbB2-erbB3 receptor complex in schwann cells. Biochem Biophys Res Commun 271:414-7
Trinidad, J C; Fischbach, G D; Cohen, J B (2000) The Agrin/MuSK signaling pathway is spatially segregated from the neuregulin/ErbB receptor signaling pathway at the neuromuscular junction. J Neurosci 20:8762-70

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