Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS020402-14
Application #
2263854
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1983-06-01
Project End
1999-08-31
Budget Start
1996-09-01
Budget End
1997-08-31
Support Year
14
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Wake Forest University Health Sciences
Department
Biology
Type
Schools of Medicine
DUNS #
041418799
City
Winston-Salem
State
NC
Country
United States
Zip Code
27106
Kim, Woon Ryoung; Chun, Sung Kun; Kim, Tae Woo et al. (2011) Evidence for the spontaneous production but massive programmed cell death of new neurons in the subcallosal zone of the postnatal mouse brain. Eur J Neurosci 33:599-611
Kim, Woon Ryoung; Park, Ok-Hee; Choi, Sukwoo et al. (2009) The maintenance of specific aspects of neuronal function and behavior is dependent on programmed cell death of adult-generated neurons in the dentate gyrus. Eur J Neurosci 29:1408-21
Oppenheim, Ronald W; Blomgren, Klas; Ethell, Douglas W et al. (2008) Developing postmitotic mammalian neurons in vivo lacking Apaf-1 undergo programmed cell death by a caspase-independent, nonapoptotic pathway involving autophagy. J Neurosci 28:1490-7
Jung, A-Rong; Kim, Tae Woo; Rhyu, Im Joo et al. (2008) Misplacement of Purkinje cells during postnatal development in Bax knock-out mice: a novel role for programmed cell death in the nervous system? J Neurosci 28:2941-8
Kim, Woon Ryoung; Kim, Younghwa; Eun, Bokkee et al. (2007) Impaired migration in the rostral migratory stream but spared olfactory function after the elimination of programmed cell death in Bax knock-out mice. J Neurosci 27:14392-403
Park, Ok-hee; Lee, Kea Joo; Rhyu, Im Joo et al. (2007) Bax-dependent and -independent death of motoneurons after facial nerve injury in adult mice. Eur J Neurosci 26:1421-32
Sato, N; Sakuma, C; Sato, Y et al. (2006) Distinct susceptibility of developing neurons to death following Bax overexpression in the chicken embryo. Cell Death Differ 13:435-45
Winseck, Adam K; Oppenheim, Ronald W (2006) An in vivo analysis of Schwann cell programmed cell death in embryonic mice: the role of axons, glial growth factor, and the pro-apoptotic gene Bax. Eur J Neurosci 24:2105-17
Buss, Robert R; Gould, Thomas W; Ma, Jianjun et al. (2006) Neuromuscular development in the absence of programmed cell death: phenotypic alteration of motoneurons and muscle. J Neurosci 26:13413-27
Sun, Woong; Gould, Thomas W; Newbern, Jason et al. (2005) Phosphorylation of c-Jun in avian and mammalian motoneurons in vivo during programmed cell death: an early reversible event in the apoptotic cascade. J Neurosci 25:5595-603

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