Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS021169-09
Application #
2264091
Study Section
Neurology A Study Section (NEUA)
Program Officer
Jacobs, Tom P
Project Start
1985-07-01
Project End
1998-05-27
Budget Start
1996-06-01
Budget End
1998-05-27
Support Year
9
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of New Mexico
Department
Neurology
Type
Schools of Medicine
DUNS #
829868723
City
Albuquerque
State
NM
Country
United States
Zip Code
87131
Yang, Yi; Rosenberg, Gary A (2011) Blood-brain barrier breakdown in acute and chronic cerebrovascular disease. Stroke 42:3323-8
Lo, Eng H; Rosenberg, Gary A (2009) The neurovascular unit in health and disease: introduction. Stroke 40:S2-3
Jian Liu, K; Rosenberg, Gary A (2005) Matrix metalloproteinases and free radicals in cerebral ischemia. Free Radic Biol Med 39:71-80
Wetzel, M; Tibbitts, J; Rosenberg, G A et al. (2004) Vulnerability of mouse cortical neurons to doxorubicin-induced apoptosis is strain-dependent and is correlated with mRNAs encoding Fas, Fas-Ligand, and metalloproteinases. Apoptosis 9:649-56
Adair, John C; Charlie, Julius; Dencoff, John E et al. (2004) Measurement of gelatinase B (MMP-9) in the cerebrospinal fluid of patients with vascular dementia and Alzheimer disease. Stroke 35:e159-62
Gursoy-Ozdemir, Yasemin; Qiu, Jianhua; Matsuoka, Norihiro et al. (2004) Cortical spreading depression activates and upregulates MMP-9. J Clin Invest 113:1447-55
Pfefferkorn, Thomas; Rosenberg, Gary A (2003) Closure of the blood-brain barrier by matrix metalloproteinase inhibition reduces rtPA-mediated mortality in cerebral ischemia with delayed reperfusion. Stroke 34:2025-30
Wetzel, M; Rosenberg, G A; Cunningham, L A (2003) Tissue inhibitor of metalloproteinases-3 and matrix metalloproteinase-3 regulate neuronal sensitivity to doxorubicin-induced apoptosis. Eur J Neurosci 18:1050-60
Mun-Bryce, Sheila; Lukes, Anton; Wallace, James et al. (2002) Stromelysin-1 and gelatinase A are upregulated before TNF-alpha in LPS-stimulated neuroinflammation. Brain Res 933:42-9
Rosenberg, Gary A (2002) Matrix metalloproteinases and neuroinflammation in multiple sclerosis. Neuroscientist 8:586-95

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