Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS022150-10
Application #
2264397
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1985-04-01
Project End
1998-02-28
Budget Start
1996-03-01
Budget End
1997-02-28
Support Year
10
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Columbia University (N.Y.)
Department
Anatomy/Cell Biology
Type
Schools of Medicine
DUNS #
167204994
City
New York
State
NY
Country
United States
Zip Code
10032
Sung, Y J; Chiu, D T W; Ambron, R T (2006) Activation and retrograde transport of protein kinase G in rat nociceptive neurons after nerve injury and inflammation. Neuroscience 141:697-709
Sung, Ying-Ju; Wu, Fang; Schacher, Samuel et al. (2006) Synaptogenesis regulates axotomy-induced activation of c-Jun-activator protein-1 transcription. J Neurosci 26:6439-49
Colby, Geoffrey P; Sung, Ying-Ju; Ambron, Richard T (2005) mRNAs encoding the Aplysia homologues of fasciclin-I and beta-thymosin are expressed only in the second phase of nerve injury and are differentially segregated in axons regenerating in vitro and in vivo. J Neurosci Res 82:484-98
Sung, Ying-Ju; Ambron, Richard T (2004) Pathways that elicit long-term changes in gene expression in nociceptive neurons following nerve injury: contributions to neuropathic pain. Neurol Res 26:195-203
Sung, Ying-Ju; Walters, Edgar T; Ambron, Richard T (2004) A neuronal isoform of protein kinase G couples mitogen-activated protein kinase nuclear import to axotomy-induced long-term hyperexcitability in Aplysia sensory neurons. J Neurosci 24:7583-95
Lin, Hana; Bao, Jianxin; Sung, Ying-Ju et al. (2003) Rapid electrical and delayed molecular signals regulate the serum response element after nerve injury: convergence of injury and learning signals. J Neurobiol 57:204-20
Farr, M; Zhu, D F; Povelones, M et al. (2001) Direct interactions between immunocytes and neurons after axotomy in Aplysia. J Neurobiol 46:89-96
Sung, Y J; Povelones, M; Ambron, R T (2001) RISK-1: a novel MAPK homologue in axoplasm that is activated and retrogradely transported after nerve injury. J Neurobiol 47:67-79
Zhang, X P; Ambron, R T (2000) Positive injury signals induce growth and prolong survival in Aplysia neurons. J Neurobiol 45:84-94
Farr, M; Mathews, J; Zhu, D F et al. (1999) Inflammation causes a long-term hyperexcitability in the nociceptive sensory neurons of Aplysia. Learn Mem 6:331-40

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