Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS023877-12
Application #
2264978
Study Section
Physiology Study Section (PHY)
Project Start
1985-12-01
Project End
1999-07-31
Budget Start
1996-08-01
Budget End
1997-07-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Physiology
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Kuryshev, Y A; Wible, B A; Gudz, T I et al. (2001) KChAP/Kvbeta1.2 interactions and their effects on cardiac Kv channel expression. Am J Physiol Cell Physiol 281:C290-9
Bianchi, L; Priori, S G; Napolitano, C et al. (2000) Mechanisms of I(Ks) suppression in LQT1 mutants. Am J Physiol Heart Circ Physiol 279:H3003-11
Kuryshev, Y A; Gudz, T I; Brown, A M et al. (2000) KChAP as a chaperone for specific K(+) channels. Am J Physiol Cell Physiol 278:C931-41
Bianchi, L; Shen, Z; Dennis, A T et al. (1999) Cellular dysfunction of LQT5-minK mutants: abnormalities of IKs, IKr and trafficking in long QT syndrome. Hum Mol Genet 8:1499-507
Accili, E A; Kuryshev, Y A; Wible, B A et al. (1998) Separable effects of human Kvbeta1.2 N- and C-termini on inactivation and expression of human Kv1.4. J Physiol 512 ( Pt 2):325-36
Wible, B A; Yang, Q; Kuryshev, Y A et al. (1998) Cloning and expression of a novel K+ channel regulatory protein, KChAP. J Biol Chem 273:11745-51
Kramer, J W; Post, M A; Brown, A M et al. (1998) Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 alpha-subunits. Am J Physiol 274:C1501-10
Dumaine, R; Roy, M L; Brown, A M (1998) Blockade of HERG and Kv1.5 by ketoconazole. J Pharmacol Exp Ther 286:727-35
Accili, E A; Kiehn, J; Wible, B A et al. (1997) Interactions among inactivating and noninactivating Kvbeta subunits, and Kvalpha1.2, produce potassium currents with intermediate inactivation. J Biol Chem 272:28232-6
Accili, E A; Kiehn, J; Yang, Q et al. (1997) Separable Kvbeta subunit domains alter expression and gating of potassium channels. J Biol Chem 272:25824-31

Showing the most recent 10 out of 60 publications