Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS024672-12
Application #
2265307
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1986-12-01
Project End
1998-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
12
Fiscal Year
1996
Total Cost
Indirect Cost
Name
University of Colorado Denver
Department
Biology
Type
Schools of Medicine
DUNS #
065391526
City
Aurora
State
CO
Country
United States
Zip Code
80045
Pfenninger, Karl H; Laurino, Lisandro; Peretti, Diego et al. (2003) Regulation of membrane expansion at the nerve growth cone. J Cell Sci 116:1209-17
Mikule, Keith; Gatlin, Jesse C; de la Houssaye, Becky A et al. (2002) Growth cone collapse induced by semaphorin 3A requires 12/15-lipoxygenase. J Neurosci 22:4932-41
Ross, S; Essary, B; de la Houssaye, B A et al. (2000) Thrombin causes pseudopod detachment via a pathway involving cytosolic phospholipase A2 and 12/15-lipoxygenase products. Cell Growth Differ 11:19-30
de La Houssaye, B A; Mikule, K; Nikolic, D et al. (1999) Thrombin-induced growth cone collapse: involvement of phospholipase A(2) and eicosanoid generation. J Neurosci 19:10843-55
Helmke, S; Lohse, K; Mikule, K et al. (1998) SRC binding to the cytoskeleton, triggered by growth cone attachment to laminin, is protein tyrosine phosphatase-dependent. J Cell Sci 111 ( Pt 16):2465-75
Mascotti, F; Caceres, A; Pfenninger, K H et al. (1997) Expression and distribution of IGF-1 receptors containing a beta-subunit variant (betagc) in developing neurons. J Neurosci 17:1447-59
Negre-Aminou, P; Nemenoff, R A; Wood, M R et al. (1996) Characterization of phospholipase A2 activity enriched in the nerve growth cone. J Neurochem 67:2599-608
Lohse, K; Helmke, S M; Wood, M R et al. (1996) Axonal origin and purity of growth cones isolated from fetal rat brain. Brain Res Dev Brain Res 96:83-96
Quiroga, S; Garofalo, R S; Pfenninger, K H (1995) Insulin-like growth factor I receptors of fetal brain are enriched in nerve growth cones and contain a beta-subunit variant. Proc Natl Acad Sci U S A 92:4309-12
Negre-Aminou, P; Pfenninger, K H (1993) Arachidonic acid turnover and phospholipase A2 activity in neuronal growth cones. J Neurochem 60:1126-36

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