Funding Agency

Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS027214-07
Application #
2266329
Study Section
Neurology A Study Section (NEUA)
Project Start
1989-04-01
Project End
1997-03-31
Budget Start
1995-04-01
Budget End
1997-03-31
Support Year
7
Fiscal Year
1995
Total Cost
Indirect Cost

  Institution

Name
Virginia Commonwealth University
Department
Pharmacology
Type
Schools of Medicine
DUNS #
City
Richmond
State
VA
Country
United States
Zip Code
23298

  Publications

Ellis, Earl F; Willoughby, Karen A; Sparks, Sallie A et al. (2007) S100B protein is released from rat neonatal neurons, astrocytes, and microglia by in vitro trauma and anti-S100 increases trauma-induced delayed neuronal injury and negates the protective effect of exogenous S100B on neurons. J Neurochem 101:1463-70
Willoughby, Karen A; Kleindienst, Andrea; Muller, Christian et al. (2004) S100B protein is released by in vitro trauma and reduces delayed neuronal injury. J Neurochem 91:1284-91
Floyd, Candace L; Rzigalinski, Beverly A; Sitterding, Heather A et al. (2004) Antagonism of group I metabotropic glutamate receptors and PLC attenuates increases in inositol trisphosphate and reduces reactive gliosis in strain-injured astrocytes. J Neurotrauma 21:205-16
Chen, Tao; Willoughby, Karen A; Ellis, Earl F (2004) Group I metabotropic receptor antagonism blocks depletion of calcium stores and reduces potentiated capacitative calcium entry in strain-injured neurons and astrocytes. J Neurotrauma 21:271-81
Goforth, Paulette B; Ellis, Earl F; Satin, Leslie S (2004) Mechanical injury modulates AMPA receptor kinetics via an NMDA receptor-dependent pathway. J Neurotrauma 21:719-32
Neary, Joseph T; Kang, Yuan; Willoughby, Karen A et al. (2003) Activation of extracellular signal-regulated kinase by stretch-induced injury in astrocytes involves extracellular ATP and P2 purinergic receptors. J Neurosci 23:2348-56
Weber, John T; Rzigalinski, Beverly A; Ellis, Earl F (2002) Calcium responses to caffeine and muscarinic receptor agonists are altered in traumatically injured neurons. J Neurotrauma 19:1433-43
Ahmed, Syed M; Weber, John T; Liang, Shi et al. (2002) NMDA receptor activation contributes to a portion of the decreased mitochondrial membrane potential and elevated intracellular free calcium in strain-injured neurons. J Neurotrauma 19:1619-29
Floyd, C L; Rzigalinski, B A; Weber, J T et al. (2001) Traumatic injury of cultured astrocytes alters inositol (1,4,5)-trisphosphate-mediated signaling. Glia 33:12-23
Weber, J T; Rzigalinski, B A; Ellis, E F (2001) Traumatic injury of cortical neurons causes changes in intracellular calcium stores and capacitative calcium influx. J Biol Chem 276:1800-7

Showing the most recent 10 out of 39 publications