Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS028384-06
Application #
2266898
Study Section
Neurology C Study Section (NEUC)
Project Start
1991-01-01
Project End
2001-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
6
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Massachusetts General Hospital
Department
Type
DUNS #
City
Boston
State
MA
Country
United States
Zip Code
02199
Jinnah, H A; Hess, Ellen J (2008) Experimental therapeutics for dystonia. Neurotherapeutics 5:198-209
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Hewett, Jeffrey W; Zeng, Juan; Niland, Brian P et al. (2006) Dystonia-causing mutant torsinA inhibits cell adhesion and neurite extension through interference with cytoskeletal dynamics. Neurobiol Dis 22:98-111
Kock, Norman; Allchorne, Andrew J; Sena-Esteves, Miguel et al. (2006) RNAi blocks DYT1 mutant torsinA inclusions in neurons. Neurosci Lett 395:201-5
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Sharma, Nutan; Baxter, Mark G; Petravicz, Jeremy et al. (2005) Impaired motor learning in mice expressing torsinA with the DYT1 dystonia mutation. J Neurosci 25:5351-5
Augood, Sarah J; Hollingsworth, Z; Albers, David S et al. (2004) Dopamine transmission in DYT1 dystonia. Adv Neurol 94:53-60
Hewett, Jeffrey W; Kamm, Christoph; Boston, Heather et al. (2004) TorsinB--perinuclear location and association with torsinA. J Neurochem 89:1186-94
Grandi, Paola; Wang, Samuel; Schuback, Deborah et al. (2004) HSV-1 virions engineered for specific binding to cell surface receptors. Mol Ther 9:419-27
Bragg, D C; Camp, S M; Kaufman, C A et al. (2004) Perinuclear biogenesis of mutant torsin-A inclusions in cultured cells infected with tetracycline-regulated herpes simplex virus type 1 amplicon vectors. Neuroscience 125:651-61

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