Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS028710-02
Application #
3415295
Study Section
Neurology C Study Section (NEUC)
Project Start
1990-08-01
Project End
1993-07-31
Budget Start
1991-08-01
Budget End
1992-07-31
Support Year
2
Fiscal Year
1991
Total Cost
Indirect Cost
Name
California Institute of Technology
Department
Type
Schools of Arts and Sciences
DUNS #
078731668
City
Pasadena
State
CA
Country
United States
Zip Code
91125
Kennedy, Mary B (2017) Biochemistry and neuroscience: the twain need to meet. Curr Opin Neurobiol 43:79-86
Wang, Shiyi; Stanika, Ruslan I; Wang, Xiaohan et al. (2017) Densin-180 Controls the Trafficking and Signaling of L-Type Voltage-Gated Cav1.2 Ca2+ Channels at Excitatory Synapses. J Neurosci 37:4679-4691
Muhia, Mary; Willadt, Silvia; Yee, Benjamin K et al. (2012) Molecular and behavioral changes associated with adult hippocampus-specific SynGAP1 knockout. Learn Mem 19:268-81
Carlisle, Holly J; Luong, Tinh N; Medina-Marino, Andrew et al. (2011) Deletion of densin-180 results in abnormal behaviors associated with mental illness and reduces mGluR5 and DISC1 in the postsynaptic density fraction. J Neurosci 31:16194-207
Marcora, Edoardo; Kennedy, Mary B (2010) The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-ýýB from the synapse to the nucleus. Hum Mol Genet 19:4373-84
Knuesel, Irene; Elliott, Abigail; Chen, Hong-Jung et al. (2005) A role for synGAP in regulating neuronal apoptosis. Eur J Neurosci 21:611-21
Carlisle, Holly J; Kennedy, Mary B (2005) Spine architecture and synaptic plasticity. Trends Neurosci 28:182-7
Vazquez, Luis E; Chen, Hong-Jung; Sokolova, Irina et al. (2004) SynGAP regulates spine formation. J Neurosci 24:8862-72
Oh, Jeong S; Manzerra, Pasquale; Kennedy, Mary B (2004) Regulation of the neuron-specific Ras GTPase-activating protein, synGAP, by Ca2+/calmodulin-dependent protein kinase II. J Biol Chem 279:17980-8
Moon, I S; Park, I S; Schenker, L T et al. (2001) Presence of both constitutive and inducible forms of heat shock protein 70 in the cerebral cortex and hippocampal synapses. Cereb Cortex 11:238-48

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