Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS029868-01A2S1
Application #
3416785
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1993-01-01
Project End
1995-12-31
Budget Start
1993-08-17
Budget End
1993-12-31
Support Year
1
Fiscal Year
1993
Total Cost
Indirect Cost
Name
Children's Hospital of Philadelphia
Department
Type
DUNS #
073757627
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Sengupta, Shaon; Yang, Guang; O'Donnell, John C et al. (2016) The circadian gene Rev-erb? improves cellular bioenergetics and provides preconditioning for protection against oxidative stress. Free Radic Biol Med 93:177-89
Susarla, Bala T S; Robinson, Michael B (2008) Internalization and degradation of the glutamate transporter GLT-1 in response to phorbol ester. Neurochem Int 52:709-22
Sheldon, Amanda L; Gonzalez, Marco I; Krizman-Genda, Elizabeth N et al. (2008) Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1. Neurochem Int 53:296-308
Sheldon, Amanda L; Robinson, Michael B (2007) The role of glutamate transporters in neurodegenerative diseases and potential opportunities for intervention. Neurochem Int 51:333-55
Sheldon, Amanda L; Gonzalez, Marco I; Robinson, Michael B (2006) A carboxyl-terminal determinant of the neuronal glutamate transporter, EAAC1, is required for platelet-derived growth factor-dependent trafficking. J Biol Chem 281:4876-86
Gonzalez, Marco I; Susarla, Bala T S; Robinson, Michael B (2005) Evidence that protein kinase Calpha interacts with and regulates the glial glutamate transporter GLT-1. J Neurochem 94:1180-8
Gonzalez, Marco I; Robinson, Michael B (2004) Protein kinase C-dependent remodeling of glutamate transporter function. Mol Interv 4:48-58
Gonzalez, Marco I; Robinson, Michael B (2004) Neurotransmitter transporters: why dance with so many partners? Curr Opin Pharmacol 4:30-5
Susarla, Bala T S; Seal, Rebecca P; Zelenaia, Olga et al. (2004) Differential regulation of GLAST immunoreactivity and activity by protein kinase C: evidence for modification of amino and carboxyl termini. J Neurochem 91:1151-63
Susarla, Bala T S; Robinson, Michael B (2003) Rottlerin, an inhibitor of protein kinase Cdelta (PKCdelta), inhibits astrocytic glutamate transport activity and reduces GLAST immunoreactivity by a mechanism that appears to be PKCdelta-independent. J Neurochem 86:635-45

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