Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS030219-12
Application #
6797141
Study Section
Special Emphasis Panel (ZRG1-MDCN-4 (01))
Program Officer
Talley, Edmund M
Project Start
1991-09-30
Project End
2006-08-31
Budget Start
2004-09-01
Budget End
2006-08-31
Support Year
12
Fiscal Year
2004
Total Cost
$297,000
Indirect Cost
Name
University of Maryland Baltimore
Department
Physiology
Type
Schools of Medicine
DUNS #
188435911
City
Baltimore
State
MD
Country
United States
Zip Code
21201
Reich, C G; Mohammadi, M H; Alger, B E (2008) Endocannabinoid modulation of fear responses: learning and state-dependent performance effects. J Psychopharmacol 22:769-77
Edwards, David A; Zhang, Longhua; Alger, Bradley E (2008) Metaplastic control of the endocannabinoid system at inhibitory synapses in hippocampus. Proc Natl Acad Sci U S A 105:8142-7
Karson, Miranda A; Whittington, Kevin C; Alger, Bradley E (2008) Cholecystokinin inhibits endocannabinoid-sensitive hippocampal IPSPs and stimulates others. Neuropharmacology 54:117-28
Isokawa, Masako; Alger, Bradley E (2006) Ryanodine receptor regulates endogenous cannabinoid mobilization in the hippocampus. J Neurophysiol 95:3001-11
Edwards, David A; Kim, Jimok; Alger, Bradley E (2006) Multiple mechanisms of endocannabinoid response initiation in hippocampus. J Neurophysiol 95:67-75
Reich, Christian G; Karson, Miranda A; Karnup, Sergei V et al. (2005) Regulation of IPSP theta rhythm by muscarinic receptors and endocannabinoids in hippocampus. J Neurophysiol 94:4290-9
Heinbockel, Thomas; Brager, Darrin H; Reich, Christian G et al. (2005) Endocannabinoid signaling dynamics probed with optical tools. J Neurosci 25:9449-59
Reich, Christian G; Mason, Susanne E; Alger, Bradley E (2004) Novel form of LTD induced by transient, partial inhibition of the Na,K-pump in rat hippocampal CA1 cells. J Neurophysiol 91:239-47
Kim, Jimok; Alger, Bradley E (2004) Inhibition of cyclooxygenase-2 potentiates retrograde endocannabinoid effects in hippocampus. Nat Neurosci 7:697-8
Brager, Darrin H; Luther, Paul W; Erdelyi, Ferenc et al. (2003) Regulation of exocytosis from single visualized GABAergic boutons in hippocampal slices. J Neurosci 23:10475-86

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