Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS030243-10
Application #
6393494
Study Section
Special Emphasis Panel (ZRG1-MDCN-3 (01))
Program Officer
Finkelstein, Robert
Project Start
1991-09-30
Project End
2004-03-31
Budget Start
2001-04-01
Budget End
2002-03-31
Support Year
10
Fiscal Year
2001
Total Cost
$312,000
Indirect Cost
Name
University of Massachusetts Medical School Worcester
Department
Psychiatry
Type
Schools of Medicine
DUNS #
660735098
City
Worcester
State
MA
Country
United States
Zip Code
01655
Liu, Liwang; Hendrickson, Linzy M; Guildford, Melissa J et al. (2013) Nicotinic acetylcholine receptors containing the ?4 subunit modulate alcohol reward. Biol Psychiatry 73:738-46
Liu, Liwang; Zhao-Shea, Rubing; McIntosh, J Michael et al. (2012) Nicotine persistently activates ventral tegmental area dopaminergic neurons via nicotinic acetylcholine receptors containing ?4 and ?6 subunits. Mol Pharmacol 81:541-8
Hendrickson, Linzy M; Gardner, Paul; Tapper, Andrew R (2011) Nicotinic acetylcholine receptors containing the ýý4 subunit are critical for the nicotine-induced reduction of acute voluntary ethanol consumption. Channels (Austin) 5:124-7
Zhao-Shea, Rubing; Liu, Liwang; Soll, Lindsey G et al. (2011) Nicotine-mediated activation of dopaminergic neurons in distinct regions of the ventral tegmental area. Neuropsychopharmacology 36:1021-32
Improgo, Ma Reina D; Schlichting, Nicolette A; Cortes, Roxana Y et al. (2010) ASCL1 regulates the expression of the CHRNA5/A3/B4 lung cancer susceptibility locus. Mol Cancer Res 8:194-203
Bruschweiler-Li, L; Fuentes Medel, Y F; Scofield, M D et al. (2010) Temporally- and spatially-regulated transcriptional activity of the nicotinic acetylcholine receptor beta4 subunit gene promoter. Neuroscience 166:864-77
Improgo, M R D; Scofield, M D; Tapper, A R et al. (2010) From smoking to lung cancer: the CHRNA5/A3/B4 connection. Oncogene 29:4874-84
Improgo, Ma Reina D; Scofield, Michael D; Tapper, Andrew R et al. (2010) The nicotinic acetylcholine receptor CHRNA5/A3/B4 gene cluster: dual role in nicotine addiction and lung cancer. Prog Neurobiol 92:212-26
Hendrickson, Linzy M; Zhao-Shea, Rubing; Pang, Xueyan et al. (2010) Activation of alpha4* nAChRs is necessary and sufficient for varenicline-induced reduction of alcohol consumption. J Neurosci 30:10169-76
Scofield, M D; Tapper, A R; Gardner, P D (2010) A transcriptional regulatory element critical for CHRNB4 promoter activity in vivo. Neuroscience 170:1056-64

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