Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS030591-01S1
Application #
3417507
Study Section
Neurological Sciences Subcommittee 1 (NLS)
Project Start
1992-05-01
Project End
1995-04-30
Budget Start
1992-07-15
Budget End
1993-04-30
Support Year
1
Fiscal Year
1992
Total Cost
Indirect Cost
Name
Children's Hospital Boston
Department
Type
DUNS #
076593722
City
Boston
State
MA
Country
United States
Zip Code
02115
Estevez, A Y; Bond, T; Strange, K (2001) Regulation of I(Cl,swell) in neuroblastoma cells by G protein signaling pathways. Am J Physiol Cell Physiol 281:C89-98
Strange, K; Singer, T D; Morrison, R et al. (2000) Dependence of KCC2 K-Cl cotransporter activity on a conserved carboxy terminus tyrosine residue. Am J Physiol Cell Physiol 279:C860-7
Bond, T; Basavappa, S; Christensen, M et al. (1999) ATP dependence of the ICl,swell channel varies with rate of cell swelling. Evidence for two modes of channel activation. J Gen Physiol 113:441-56
Wu, Q; Delpire, E; Hebert, S C et al. (1998) Functional demonstration of Na+-K+-2Cl- cotransporter activity in isolated, polarized choroid plexus cells. Am J Physiol 275:C1565-72
Kirk, K; Strange, K (1998) Functional properties and physiological roles of organic solute channels. Annu Rev Physiol 60:719-39
Cannon, C L; Basavappa, S; Strange, K (1998) Intracellular ionic strength regulates the volume sensitivity of a swelling-activated anion channel. Am J Physiol 275:C416-22
Strange, K (1998) Molecular identity of the outwardly rectifying, swelling-activated anion channel: time to reevaluate pICln. J Gen Physiol 111:617-22
Emma, F; Sanchez-Olea, R; Strange, K (1998) Characterization of pI(Cln) binding proteins: identification of p17 and assessment of the role of acidic domains in mediating protein-protein interactions. Biochim Biophys Acta 1404:321-8
Emma, F; Breton, S; Morrison, R et al. (1998) Effect of cell swelling on membrane and cytoplasmic distribution of pICln. Am J Physiol 274:C1545-51
Sanchez-Olea, R; Emma, F; Coghlan, M et al. (1998) Characterization of pICln phosphorylation state and a pICln-associated protein kinase. Biochim Biophys Acta 1381:49-60

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