Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
5R01NS030800-02
Application #
2268768
Study Section
Neurology B Subcommittee 2 (NEUB)
Project Start
1995-01-01
Project End
1997-12-31
Budget Start
1996-01-01
Budget End
1996-12-31
Support Year
2
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Case Western Reserve University
Department
Neurosciences
Type
Schools of Medicine
DUNS #
077758407
City
Cleveland
State
OH
Country
United States
Zip Code
44106
Luo, Fucheng; Zhang, Jessie; Burke, Kathryn et al. (2018) Oligodendrocyte-specific loss of Cdk5 disrupts the architecture of nodes of Ranvier as well as learning and memory. Exp Neurol 306:92-104
Sargent, Alex; Shano, Genevieve; Karl, Molly et al. (2018) Transcriptional Profiling of Mesenchymal Stem Cells Identifies Distinct Neuroimmune Pathways Altered by CNS Disease. Int J Stem Cells 11:48-60
Sargent, Alex; Bai, Lianhua; Shano, Genevieve et al. (2017) CNS disease diminishes the therapeutic functionality of bone marrow mesenchymal stem cells. Exp Neurol 295:222-232
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Luo, Fucheng; Zhang, Jessie; Burke, Kathryn et al. (2016) The Activators of Cyclin-Dependent Kinase 5 p35 and p39 Are Essential for Oligodendrocyte Maturation, Process Formation, and Myelination. J Neurosci 36:3024-37
Sargent, Alex; Miller, Robert H (2016) MSC Therapeutics in Chronic Inflammation. Curr Stem Cell Rep 2:168-173
Tognatta, Reshmi; Miller, Robert H (2016) Contribution of the oligodendrocyte lineage to CNS repair and neurodegenerative pathologies. Neuropharmacology 110:539-547
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Zuchero, J Bradley; Fu, Meng-Meng; Sloan, Steven A et al. (2015) CNS myelin wrapping is driven by actin disassembly. Dev Cell 34:152-67
Najm, Fadi J; Madhavan, Mayur; Zaremba, Anita et al. (2015) Drug-based modulation of endogenous stem cells promotes functional remyelination in vivo. Nature 522:216-20

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