Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
1R01NS035107-01
Application #
2274437
Study Section
Special Emphasis Panel (ZRG1-NLS-3 (01))
Project Start
1996-05-01
Project End
1999-04-30
Budget Start
1996-05-01
Budget End
1997-04-30
Support Year
1
Fiscal Year
1996
Total Cost
Indirect Cost
Name
Washington University
Department
Pathology
Type
Schools of Medicine
DUNS #
062761671
City
Saint Louis
State
MO
Country
United States
Zip Code
63130
Mader, Burton J; Pivtoraiko, Violetta N; Flippo, Hilary M et al. (2012) Rotenone inhibits autophagic flux prior to inducing cell death. ACS Chem Neurosci 3:1063-72
Ghosh, Arindam P; Klocke, Barbara J; Ballestas, Mary E et al. (2012) CHOP potentially co-operates with FOXO3a in neuronal cells to regulate PUMA and BIM expression in response to ER stress. PLoS One 7:e39586
Kaza, Niroop; Kohli, Latika; Roth, Kevin A (2012) Autophagy in brain tumors: a new target for therapeutic intervention. Brain Pathol 22:89-98
Ghosh, Arindam P; Cape, Jennifer D; Klocke, Barbara J et al. (2011) Deficiency of pro-apoptotic Hrk attenuates programmed cell death in the developing murine nervous system but does not affect Bcl-x deficiency-induced neuron apoptosis. J Histochem Cytochem 59:976-83
Geng, Ying; Kohli, Latika; Klocke, Barbara J et al. (2010) Chloroquine-induced autophagic vacuole accumulation and cell death in glioma cells is p53 independent. Neuro Oncol 12:473-81
Walls, Ken C; Ghosh, Arindam P; Franklin, Aimee V et al. (2010) Lysosome dysfunction triggers Atg7-dependent neural apoptosis. J Biol Chem 285:10497-507
Pivtoraiko, Violetta N; Harrington, Adam J; Mader, Burton J et al. (2010) Low-dose bafilomycin attenuates neuronal cell death associated with autophagy-lysosome pathway dysfunction. J Neurochem 114:1193-204
Kohli, Latika; Roth, Kevin A (2010) Autophagy: cerebral home cooking. Am J Pathol 176:1065-71
Christensen, Heather M; Dikranian, Krikor; Li, Aimin et al. (2010) A highly toxic cellular prion protein induces a novel, nonapoptotic form of neuronal death. Am J Pathol 176:2695-706
Geng, Ying; Walls, K C; Ghosh, Arindam P et al. (2010) Cytoplasmic p53 and activated Bax regulate p53-dependent, transcription-independent neural precursor cell apoptosis. J Histochem Cytochem 58:265-75

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