Agency
National Institute of Health (NIH)
Institute
National Institute of Neurological Disorders and Stroke (NINDS)
Type
Research Project (R01)
Project #
3R01NS045021-01S1
Application #
6804747
Study Section
Special Emphasis Panel (ZRG1)
Program Officer
Finkelstein, Robert
Project Start
2003-01-01
Project End
2006-12-31
Budget Start
2003-01-01
Budget End
2003-12-31
Support Year
1
Fiscal Year
2003
Total Cost
$22,500
Indirect Cost
Name
University of Pennsylvania
Department
Neurology
Type
Schools of Medicine
DUNS #
042250712
City
Philadelphia
State
PA
Country
United States
Zip Code
19104
Crino, Peter B (2013) Evolving neurobiology of tuberous sclerosis complex. Acta Neuropathol 125:317-32
Prabowo, Avanita S; Anink, Jasper J; Lammens, Martin et al. (2013) Fetal brain lesions in tuberous sclerosis complex: TORC1 activation and inflammation. Brain Pathol 23:45-59
Hollidge, Bradley S; Nedelsky, Natalia B; Salzano, Mary-Virginia et al. (2012) Orthobunyavirus entry into neurons and other mammalian cells occurs via clathrin-mediated endocytosis and requires trafficking into early endosomes. J Virol 86:7988-8001
Crino, Peter B (2011) mTOR: A pathogenic signaling pathway in developmental brain malformations. Trends Mol Med 17:734-42
Parker, Whitney E; Orlova, Ksenia A; Heuer, Gregory G et al. (2011) Enhanced epidermal growth factor, hepatocyte growth factor, and vascular endothelial growth factor expression in tuberous sclerosis complex. Am J Pathol 178:296-305
Boer, Karin; Crino, Peter B; Gorter, Jan A et al. (2010) Gene expression analysis of tuberous sclerosis complex cortical tubers reveals increased expression of adhesion and inflammatory factors. Brain Pathol 20:704-19
Crino, Peter B; Aronica, Eleonora; Baltuch, Gordon et al. (2010) Biallelic TSC gene inactivation in tuberous sclerosis complex. Neurology 74:1716-23
Orlova, Ksenia A; Tsai, Victoria; Baybis, Marianna et al. (2010) Early progenitor cell marker expression distinguishes type II from type I focal cortical dysplasias. J Neuropathol Exp Neurol 69:850-63
Crino, Peter B (2010) The pathophysiology of tuberous sclerosis complex. Epilepsia 51 Suppl 1:27-9
Marcotte, Leah; Crino, Peter B (2006) The neurobiology of the tuberous sclerosis complex. Neuromolecular Med 8:531-46

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