Agency
National Institute of Health (NIH)
Institute
National Center for Research Resources (NCRR)
Type
Research Project (R01)
Project #
5R01RR011114-08
Application #
6639863
Study Section
Special Emphasis Panel (ZRG1-MDCN-3 (01))
Program Officer
Farber, Gregory K
Project Start
1996-04-15
Project End
2005-03-31
Budget Start
2003-04-01
Budget End
2004-03-31
Support Year
8
Fiscal Year
2003
Total Cost
$385,000
Indirect Cost
Name
State University of New York at Buffalo
Department
Physiology
Type
Schools of Medicine
DUNS #
038633251
City
Buffalo
State
NY
Country
United States
Zip Code
14260
Ryu, Sujung; Liu, Beiying; Yao, Jing et al. (2007) Uncoupling proton activation of vanilloid receptor TRPV1. J Neurosci 27:12797-807
Milescu, Lorin S; Yildiz, Ahmet; Selvin, Paul R et al. (2006) Extracting dwell time sequences from processive molecular motor data. Biophys J 91:3135-50
Milescu, Lorin S; Yildiz, Ahmet; Selvin, Paul R et al. (2006) Maximum likelihood estimation of molecular motor kinetics from staircase dwell-time sequences. Biophys J 91:1156-68
Milescu, Lorin S; Akk, Gustav; Sachs, Frederick (2005) Maximum likelihood estimation of ion channel kinetics from macroscopic currents. Biophys J 88:2494-515
Liu, Beiying; Zhang, Chunguang; Qin, Feng (2005) Functional recovery from desensitization of vanilloid receptor TRPV1 requires resynthesis of phosphatidylinositol 4,5-bisphosphate. J Neurosci 25:4835-43
Liu, Beiying; Qin, Feng (2005) Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate. J Neurosci 25:1674-81
Liu, Beiying; Ma, Weijun; Ryu, Sujung et al. (2004) Inhibitory modulation of distal C-terminal on protein kinase C-dependent phospho-regulation of rat TRPV1 receptors. J Physiol 560:627-38
Qin, Feng (2004) Restoration of single-channel currents using the segmental k-means method based on hidden Markov modeling. Biophys J 86:1488-501
Qin, Feng; Li, Ling (2004) Model-based fitting of single-channel dwell-time distributions. Biophys J 87:1657-71
Hui, Kwokyin; Liu, Beiying; Qin, Feng (2003) Capsaicin activation of the pain receptor, VR1: multiple open states from both partial and full binding. Biophys J 84:2957-68

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